2. Epigenetics
    Metabolic Enzyme/Protease
  3. DNA Methyltransferase
    Endogenous Metabolite
  4. 5-Methyl-2'-deoxycytidine

5-Methyl-2'-deoxycytidine  (Synonyms: 5-Methyldeoxycytidine)

Cat. No.: HY-W012078 Purity: 99.85%
COA Handling Instructions

5-Methyl-2'-deoxycytidine in single-stranded DNA can act in cis to signal de novo DNA methylation.

For research use only. We do not sell to patients.

5-Methyl-2'-deoxycytidine Chemical Structure

5-Methyl-2'-deoxycytidine Chemical Structure

CAS No. : 838-07-3

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Solution
10 mM * 1 mL in DMSO USD 55 In-stock
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 55 In-stock
Solid
100 mg USD 50 In-stock
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Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products

1 Publications Citing Use of MCE 5-Methyl-2'-deoxycytidine

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Description

5-Methyl-2'-deoxycytidine in single-stranded DNA can act in cis to signal de novo DNA methylation[1][2].

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

241.24

Appearance

Solid

Formula

C10H15N3O4
CAS No.
SMILES

OC[[email protected]@H]1[[email protected]@H](O)C[[email protected]](N2C(N=C(N)C(C)=C2)=O)O1
Structure Classification
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (414.52 mM)

H2O : 100 mg/mL (414.52 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.1452 mL 20.7262 mL 41.4525 mL
5 mM 0.8290 mL 4.1452 mL 8.2905 mL
10 mM 0.4145 mL 2.0726 mL 4.1452 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (414.52 mM); Clear solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (10.36 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (10.36 mM); Clear solution

  • 4.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (10.36 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: 99.85%

COA (252 KB) HNMR (123 KB) RP-HPLC (189 KB) OR (91 KB)

Handling Instructions (2659 KB)
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

5-Methyl-2'-deoxycytidine838-07-35-MethyldeoxycytidineDNA MethyltransferaseEndogenous MetaboliteDNMTsDNA MTasesInhibitorinhibitorinhibit

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