1. Epigenetics
    Metabolic Enzyme/Protease
  2. DNA Methyltransferase
    Endogenous Metabolite
  3. 5-Methyl-2'-deoxycytidine

5-Methyl-2'-deoxycytidine (Synonyms: 5-Methyldeoxycytidine)

Cat. No.: HY-W012078 Purity: 98.15%
Handling Instructions

5-Methyl-2'-deoxycytidine in single-stranded DNA can act in cis to signal de novo DNA methylation.

For research use only. We do not sell to patients.

5-Methyl-2'-deoxycytidine Chemical Structure

5-Methyl-2'-deoxycytidine Chemical Structure

CAS No. : 838-07-3

Size Price Stock Quantity
10 mM * 1  mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
100 mg USD 50 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Description

5-Methyl-2'-deoxycytidine in single-stranded DNA can act in cis to signal de novo DNA methylation[1][2].

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

241.24

Formula

C₁₀H₁₅N₃O₄

CAS No.

838-07-3

SMILES

OC[[email protected]@H]1[[email protected]](C[[email protected]](N2C(N=C(C(C)=C2)N)=O)O1)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (414.52 mM)

H2O : 100 mg/mL (414.52 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.1452 mL 20.7262 mL 41.4525 mL
5 mM 0.8290 mL 4.1452 mL 8.2905 mL
10 mM 0.4145 mL 2.0726 mL 4.1452 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (10.36 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (10.36 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (10.36 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 98.15%

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Keywords:

5-Methyl-2'-deoxycytidine5-MethyldeoxycytidineDNA MethyltransferaseEndogenous MetaboliteDNMTsDNA MTasesInhibitorinhibitorinhibit

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Product Name:
5-Methyl-2'-deoxycytidine
Cat. No.:
HY-W012078
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