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Results for "

microtubule assembly/disassembly dynamics

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-13520
    Nocodazole
    115+ Cited Publications

    Oncodazole; R17934

    		 Bcr-Abl Autophagy Microtubule/Tubulin Apoptosis Mitosis Cancer
    Nocodazole (Oncodazole) is a rapidly-reversible inhibitor of microtubule. Nocodazole binds to β-tubulin and disrupts microtubule assembly/disassembly dynamics, which prevents mitosis and induces apoptosis in tumor cells. Nocodazole inhibits Bcr-Abl.
    Nocodazole
  • HY-13520R
    Nocodazole (Standard)

    Oncodazole (Standard); R17934 (Standard)

    		 Bcr-Abl Autophagy Microtubule/Tubulin Apoptosis Mitosis Reference Standards Cancer
    Nocodazole (Standard) is the analytical standard of Nocodazole. This product is intended for research and analytical applications. Nocodazole (Oncodazole) is a rapidly-reversible inhibitor of microtubule. Nocodazole binds to β-tubulin and disrupts microtubule assembly/disassembly dynamics, which prevents mitosis and induces apoptosis in tumor cells. Nocodazole inhibits Bcr-Abl.
    Nocodazole (Standard)
  • HY-185483
    AMG-172

    		Antibody-Drug Conjugates (ADCs) Transmembrane Glycoprotein Microtubule/Tubulin Cancer
    AMG-172 is an antibody-drug conjugate (ADC) composed of a fully human IgG1 monoclonal anti-CD27L antibody conjugated to DM1 (HY-19792) via the non-cleavable linker MCC. AMG-172 releases the intracellular active component Lysine-MCC-DM through catabolism. Lysine-MCC-DM inhibits the assembly and disassembly dynamics of Microtubule and induces cell arrest at metaphase. AMG-172 can be used for research on relapsed/refractory clear cell renal cell carcinoma .
    AMG-172

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