1 Result for "

moderate liver microsomal stability

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "moderate liver microsomal stability" in MCE Product Catalog:

Cat. No.: HY-163004
Target:  

Trk Receptor

Research Areas:  

Cancer

Type II TRK inhibitor 2 (compound 40l) is a selective type II TRK inhibitor with plasma stability and moderate hepatic microsomal stability. Type II TRK inhibitor 2 significantly inhibits Km-12, Ba/F3-TRKA G595R and Ba/F3-TRKA G667C cell proliferation (IC50: 4.1 nM, 41.5 nM, 1.4 nM). Type II TRK inhibitor 2 can be used to study NTRK fusion cancers .
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