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Results for "

mouse sensory neurons

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

6

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P2847
    Urocortin II, mouse

    		CRFR Metabolic Disease Endocrinology
    Urocortin II, mouse is a potent and selective endogenous peptide agonist of type-2 corticotropin-releasing factor (CRF2) receptor with Ki values of 0.66 nM and ﹥100 nM for CRFR2 and CRFR1, respectively. Urocortin II, mouse activates CRF2 receptors in a cAMP/PKA- and Ca 2+/CaMKII-dependent manner.Urocortin II, mouse is expressed in discrete areas of the central nervous system, and activates central neurons involved in the processing of visceral sensory information, and in modulating autonomic outflow .
    Urocortin II, mouse
  • HY-163763
    T-10418

    		G2A (GPR132) Neurological Disease Inflammation/Immunology Cancer
    T-10418 is a potent and highly selective G2A/GPR132 agonist. T-10418 has an EC50 of 0.82 μM for human G2A activation. T-10418 has good water solubility, metabolic stability, and pharmacokinetic properties. T-10418 can be used for the research of various diseases such as neuropathic pain, acute myeloid leukemia, and inflammation .
    T-10418
  • HY-P11701
    SEIDLILGY

    		MHC Others
    SEIDLILGY is a nonapeptide identified as a peptide ligand derived from mouse major histocompatibility complex class I (MHC). SEIDLILGY serves as a tool chemical stimulant for the specific activation of sensory neurons expressing the particular vomeronasal receptor (V2rf2) .
    SEIDLILGY
  • HY-P11700
    AAPDARETA

    		MHC Inflammation/Immunology
    AAPDARETA is a mutated MHC-associated peptide with reduced binding affinity to H-2D b MHC molecules. AAPDARETA activates subsets of mouse main olfactory epithelium sensory neurons and induces Ca 2+ transients .
    AAPDARETA
  • HY-P11704
    f-MKKFRW

    		Formyl Peptide Receptor (FPR) Bacterial Neurological Disease
    f-MKKFRW is a selective mouse formyl peptide receptor 3 (Fpr3) activator and bacterial MgrB-derived peptide motif. f-MKKFRW activates Fpr3 to trigger downstream signaling and calcium responses in Fpr3-expressing cells. f-MKKFRW stimulates a subset of mouse vomeronasal sensory neurons in the accessory olfactory system to evoke calcium responses. f-MKKFRW drives innate avoidance behavior in mice via nasal contact .
    f-MKKFRW
  • HY-P11703
    TRVLNLGPI

    		MHC Others
    TRVLNLGPI is an MHC motif-containing, MHC-independent nonapeptide. TRVLNLGPI is not a product of immune presentation, but a product of renal protein degradation, and its concentration is sufficiently high to be specifically recognized by vomeronasal neurons. The concentration of TRVLNLGPI in mouse urine can be six orders of magnitude higher than that of prototype MHC-dependent peptides .
    TRVLNLGPI
  • HY-P11702
    f-MFFINTLTL

    		Bacterial Others
    f-MFFINTLTL is a formylated nonapeptide and a natural ligand from mitochondria or bacteria. f-MFFINTLTL serves as a tool chemical stimulant for the specific activation of sensory neurons expressing the specific vomeronasal receptor (V2rf2) .
    f-MFFINTLTL
  • HY-183857
    DD-161515

    		TRP Channel Neurological Disease
    DD-161515 is a TRPV1/VR1 inhibitor with an IC50 of 0.7 μM in rats. DD-161515 binds to an allosteric site of TRPV1 distinct from that of capsaicin, blocks channel opening, inhibits receptor-mediated calcium ion influx, reduces the excitability of peripheral sensory nerve fibers, and thereby inhibits nociception induced by heat and transmission of chemically induced pain signals. DD-161515 can be used in studies related to inflammatory pain .
    DD-161515

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