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Cat. No.: HY-P11700

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AAPDARETA

AAPDARETA is a mutated MHC-associated peptide with reduced binding affinity to H-2D^b MHC molecules. AAPDARETA activates subsets of mouse main olfactory epithelium sensory neurons and induces Ca²⁺ transients.

For research use only. We do not sell to patients.

Formula: C₃₆H₆₀N₁₂O₁₅
Molecular Weight:900.93

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

AAPDARETA Chemical Structure

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Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Protocols (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All MHC Isoforms :

MHC I
MHC II

In Vitro

AAPDARETA (10⁻¹²-10⁻⁶ M) activates subsets of mouse main olfactory epithelium sensory neurons with an EC₅₀ of 8.3 nM^[1].
AAPDARETA (10⁻⁹ M) elicits small but significant calcium transients in two-thirds of AAPDNRETF-sensitive single olfactory sensory neurons in ex vivo mouse main olfactory epithelium slices^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.

Chemical Information

Molecular Weight 900.93
Formula C₃₆H₆₀N₁₂O₁₅
Sequence

Ala-Ala-Pro-Asp-Ala-Arg-Glu-Thr-Ala
Sequence Shortening

AAPDARETA
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Cell Biology

Ca²⁺ Staining Technique
Ca²⁺ staining is an experimental technique that utilizes specific fluorescent probes (such as Fluo-4 AM, Fura-2, etc.) to qualitatively or quantitatively detect dynamic changes in intracellular Ca²⁺ concentrations; this is achieved by monitoring the changes in fluorescent signals generated when these probes bind to free intracellular calcium ions. The underlying principle relies primarily on the presence of chelating groups within the probe's molecular structure that possess high affinity for calcium ions.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (257 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Spehr M, et al. Essential role of the main olfactory system in social recognition of major histocompatibility complex peptide ligands. J Neurosci. 2006;26(7):1961-1970. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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