2 Results for "

murine BMDCs

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "murine BMDCs" in MCE Product Catalog:

  • Targets Recommended:
Cat. No.: HY-170522
CAS No.: 2924181-80-4
Synonyms: ISM012-042
Research Areas:  

Inflammation/Immunology

Garutadustat (ISM012-042) is an orally active, selective inhibitor of PHD1 and PHD2, with IC50 values of 1.9 nM and 2.5 nM, respectively. Garutadustat stabilizes HIF1α protein in intestinal epithelial cells, thereby activating gene transcription programs associated with mucus production, tight junction formation, anti-inflammatory mediator generation and wound healing, which fundamentally promotes mucosal barrier repair and regulates intestinal immunity. Garutadustat can be used for the research of inflammatory bowel disease .
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Cat. No.: HY-P11060
Synonyms: Adpgk peptide
Target:  

MHC

Research Areas:  

Cancer

MC38 SLP Adpgk (Adpgk peptide) is an H-2 K b-restricted colorectal cancer neoantigen peptide. MC38 SLP Adpgk is formulated into PCNP nanocomplexes together with CpG ODN. PCNP vaccines significantly enhance the co-delivery efficiency of neoantigens and adjuvants to lymphoid organs, and activate cytotoxic T cells. PCNP vaccines not only protect mice from MC-38 colorectal tumor invasion, but also exhibit anti-tumor efficacy in established colorectal tumor models and significantly prolong the survival of tumor-bearing mice .
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