9 Results for "

mutagenic impurity

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "mutagenic impurity" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-G0007
CAS No.: 88546-55-8
Synonyms: Omeprazole sulphone
Omeprazole sulfone (Omeprazole sulphone) is one of the major circulating metabolites of Omeprazole (HY-B0113) in vivo, and belongs to class 4 non-mutagenic impurities. Omeprazole sulfone does not bind to the aryl hydrocarbon receptor (AhR), nor does it induce the expression of CYP1A1 or CYP1A2. However, Omeprazole sulfone promotes the migration of gastric epithelial cells under basal conditions and reverses the inhibitory effect of Indomethacin (HY-14397) on cell migration. Omeprazole sulfone does not promote cell proliferation, nor does it upregulate COX-2 expression or activate signaling pathways such as ERK, P38 MAPK and PI3K. Omeprazole sulfone maintains basal ulcer healing under non-acid-dependent conditions and can be used in studies related to gastric ulcer repair .
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Cat. No.: HY-100079
CAS No.: 1446486-33-4
Purity:  96.69%
Synonyms: mutagenic impurity of tenofovir disoproxil
Target:  

Drug Intermediate

Research Areas:  

Others

9-Propenyladenine (Mutagenic impurity of tenofovir disoproxil) is a purine derivative mutagenic impurity of Tenofovir Disoproxil (HY-13782A), and also serves as a capping group intermediate in the synthesis of N-substituted purines .
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Cat. No.: HY-100079A
CAS No.: 1464851-21-5
Purity:  98.02%
Synonyms: (Z)-mutagenic impurity of Tenofovir Disoproxil
Target:  

HIV

Research Areas:  

Infection

(Z)-9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate. Tenofovir is an antiretroviral agent known as nucleotide analogue reverse transcriptase (NtART) inhibitor, which blocks reverse transcriptase, a crucial virus enzyme in HIV-1 and HBV.
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Cat. No.: HY-100079R
CAS No.: 1446486-33-4
Synonyms: mutagenic impurity of Tenofovir Disoproxil (Standard); Tenofovir impurity 2 (Standard)
Research Areas:  

Others

9-Propenyladenine (Standard) (Mutagenic Impurity of Tenofovir Disoproxil (Standard); Tenofovir Impurity 2 (Standard)) is the analytical standard of 9-Propenyladenine (HY-100079). This product is intended for research and analytical applications. 9-Propenyladenine (Mutagenic impurity of tenofovir disoproxil) is a purine derivative mutagenic impurity of Tenofovir Disoproxil (HY-13782A), and also serves as a capping group intermediate in the synthesis of N-substituted purines .
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Cat. No.: HY-179396
CAS No.: 1884551-35-2
Target:  

Bacterial

Research Areas:  

Infection

T-1228 is a highly selective LpxC inhibitor. T-1228 can effectively block the synthesis of LPS (HY-D1056), causing defects in the bacterial outer membrane structure, increasing membrane permeability, and ultimately leading to bacterial cell death. T-1228 can be used for the study of Gram-negative bacterial infections .
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Cat. No.: HY-G0007R
CAS No.: 88546-55-8
Synonyms: Omeprazole sulphone (Standard)
Omeprazole sulfone (Standard) is the analytical standard of Omeprazole sulfone. This product is intended for research and analytical applications. Omeprazole sulfone (Omeprazole sulphone) is one of the major circulating metabolites of Omeprazole (HY-B0113) in vivo, and belongs to class 4 non-mutagenic impurities. Omeprazole sulfone does not bind to the aryl hydrocarbon receptor (AhR), nor does it induce the expression of CYP1A1 or CYP1A2. However, Omeprazole sulfone promotes the migration of gastric epithelial cells under basal conditions and reverses the inhibitory effect of Indomethacin (HY-14397) on cell migration. Omeprazole sulfone does not promote cell proliferation, nor does it upregulate COX-2 expression or activate signaling pathways such as ERK, P38 MAPK and PI3K. Omeprazole sulfone maintains basal ulcer healing under non-acid-dependent conditions and can be used in studies related to gastric ulcer repair .
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Cat. No.: HY-W038877R
CAS No.: 181289-23-6
Synonyms: (S)-Pregabalin lactam (Standard)
Research Areas:  

Others

Pregabalin lactam (Standard) is an analytical standard for Pregabalin lactam. This product is used for research and analytical applications. Pregabalin lactam is a degradation product and is a common impurity with no mutagenicity .
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Cat. No.: HY-G0007S
CAS No.: 2749628-17-7
Synonyms: Omeprazole sulfone-d3; Omeprazole sulphone-d3
Omeprazole sulfone-d3 is the deuterium labeled Omeprazole sulfone. Omeprazole sulfone (Omeprazole sulphone) is one of the major circulating metabolites of Omeprazole (HY-B0113) in vivo, and belongs to class 4 non-mutagenic impurities. Omeprazole sulfone does not bind to the aryl hydrocarbon receptor (AhR), nor does it induce the expression of CYP1A1 or CYP1A2. However, Omeprazole sulfone promotes the migration of gastric epithelial cells under basal conditions and reverses the inhibitory effect of Indomethacin (HY-14397) on cell migration. Omeprazole sulfone does not promote cell proliferation, nor does it upregulate COX-2 expression or activate signaling pathways such as ERK, P38 MAPK and PI3K. Omeprazole sulfone maintains basal ulcer healing under non-acid-dependent conditions and can be used in studies related to gastric ulcer repair .
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Cat. No.: HY-G0007S1
CAS No.: 1261393-28-5
Synonyms: Omeprazole sulfone-13C,d3; Omeprazole sulphone-13C,d3
Omeprazole sulfone- 13C,d3 is the deuterium and 13C labeled Omeprazole sulfone. Omeprazole sulfone (Omeprazole sulphone) is one of the major circulating metabolites of Omeprazole (HY-B0113) in vivo, and belongs to class 4 non-mutagenic impurities. Omeprazole sulfone does not bind to the aryl hydrocarbon receptor (AhR), nor does it induce the expression of CYP1A1 or CYP1A2. However, Omeprazole sulfone promotes the migration of gastric epithelial cells under basal conditions and reverses the inhibitory effect of Indomethacin (HY-14397) on cell migration. Omeprazole sulfone does not promote cell proliferation, nor does it upregulate COX-2 expression or activate signaling pathways such as ERK, P38 MAPK and PI3K. Omeprazole sulfone maintains basal ulcer healing under non-acid-dependent conditions and can be used in studies related to gastric ulcer repair .
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