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Cat. No.: HY-G0007R

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Omeprazole sulfone (Standard)

(Synonyms: Omeprazole sulphone (Standard))

Omeprazole sulfone (Standard) is the analytical standard of Omeprazole sulfone. This product is intended for research and analytical applications. Omeprazole sulfone (Omeprazole sulphone) is one of the major circulating metabolites of Omeprazole (HY-B0113) in vivo, and belongs to class 4 non-mutagenic impurities. Omeprazole sulfone does not bind to the aryl hydrocarbon receptor (AhR), nor does it induce the expression of CYP1A1 or CYP1A2. However, Omeprazole sulfone promotes the migration of gastric epithelial cells under basal conditions and reverses the inhibitory effect of Indomethacin (HY-14397) on cell migration. Omeprazole sulfone does not promote cell proliferation, nor does it upregulate COX-2 expression or activate signaling pathways such as ERK, P38 MAPK and PI3K. Omeprazole sulfone maintains basal ulcer healing under non-acid-dependent conditions and can be used in studies related to gastric ulcer repair.

For research use only. We do not sell to patients.

CAS No.: 88546-55-8
Formula: C₁₇H₁₉N₃O₄S
Molecular Weight:361.42

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Omeprazole sulfone (Standard) Chemical Structure

CAS No.: 88546-55-8

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Chemical Information
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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 88546-55-8
Molecular Weight 361.42
Formula C₁₇H₁₉N₃O₄S
SMILES

CC(C(OC)=C(C)C=N1)=C1CS(C2=NC3=CC=C(OC)C=C3N2)(=O)=O
Synonyms

Omeprazole sulphone (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Daujat M, et al. Omeprazole, an inducer of human CYP1A1 and 1A2, is not a ligand for the Ah receptor[J]. Biochemical and biophysical research communications, 1992, 188(2): 820-825.

[2]. Ng KM, et al. Omeprazole promotes gastric epithelial cell migration. J Pharm Pharmacol. 2008;60(5):655-660. [Content Brief]

[3]. Sumer E, et al. Evaluation of toxicological profile of omeprazole degradation impurities in an intravenous drug product: omeprazole-sulfone and omeprazole-N-oxide. Drug Chem Toxicol. Published online July 28, 2025. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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