9 Results for "

nasal mucosa

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "nasal mucosa" in MCE Product Catalog:

  • Targets Recommended:
2
2 Cited Publications
Cat. No.: HY-P1014
CAS No.: 119911-68-1
Synonyms: Human α-CGRP (8-37)
Target:  

CGRP Receptor

Research Areas:  

Cardiovascular Disease

HCGRP-(8-37) (Human α-CGRP (8-37)) is a fragment of human calcitonin gene-related peptide (hCGRP) and an antagonist of the CGRP receptor, with an IC50 of 32.1 pM against the CGRP receptor. HCGRP-(8-37) blocks adenylate cyclase activation induced by CGRP receptor ligands and attenuates vascular responses triggered by CGRP. HCGRP-(8-37) reduces capsaicin-induced vasodilation in porcine nasal mucosa and superficial skin. HCGRP-(8-37) serves as a research tool to distinguish effects mediated by CGRP or calcitonin receptors, and to investigate CGRP-induced vascular effects .
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2
2 Cited Publications
Cat. No.: HY-12709A
CAS No.: 55974-42-0
Purity:  99.57%
ARC 239 dihydrochloride is a selective α2B/2C adrenoceptor antagonist (pKd values are 5.95, 7.41 and 7.56 at α2A, α2B, and α2C receptors respectively). ARC 239 dihydrochloride binds to CHO cell membranes expressing human recombinant a2A-, a2B- or a2C-adrenoceptor subtypes with pKis of 5.6, 8.4, and 7.08, respectively .
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Cat. No.: HY-78086
CAS No.: 620-23-5
Synonyms: 3-Methylbenzaldehyde
m-Tolualdehyde (3-Methylbenzaldehyde) is an aldehyde metabolite produced by m-xylene metabolism, and it bidirectionally regulates the CYP 2B1, CYP 2E1, and CYP 4B1 isoenzymes in the respiratory tract of rats. m-Tolualdehyde serves as an oxidation substrate and carbon source for Pseudomonas Pxy, and it can be oxidized to m-toluic acid in an NAD + -dependent manner. m-Tolualdehyde exerts a dose-dependent inhibitory effect on CYP 2B1 and CYP 2E1 in the nasal mucosa and lungs of rats, and a dose-dependent activating effect on pulmonary CYP 4B1. m-Tolualdehyde can form aldehyde-heme adducts with the heme group of cytochrome P450. m-Tolualdehyde can be used in studies related to metabolic enzymes in the respiratory tract of rats .
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Cat. No.: HY-116953
CAS No.: 98049-69-5
Synonyms: LXB4
Target:  

Endogenous Metabolite

Research Areas:  

Inflammation/Immunology

Lipoxin B4 (LXB4) is a structurally distinct product of arachidonic acid metabolism. Lipoxin B4 reduces leukocyte infiltration and mucus secretion in the nasal mucosa and decreases mast cell and eosinophil degranulation in the upper airway. Lipoxin B4 decreases airway inflammation, mucus metaplasia and hyper- responsiveness in the lower airway. Lipoxin B4 shows mucosal protective actions and has the potential for the research of allergic inflammation in the upper and lower airways .
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Cat. No.: HY-W015593
CAS No.: 13803-74-2
Target:  

Adrenergic Receptor

Research Areas:  

Cardiovascular Disease

Methylhexanamine hydrochloride is an aliphatic amine and a vasoconstrictor that can be administered by inhalation to the nasal mucosa to exert its effect as a nasal decongestant .
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Cat. No.: HY-171948
Target:  

Liposome

Research Areas:  

Cancer

FO-35 is an ionizable lipid that can be used to synthesize lipid nanoparticles (LNPs). FO-35 can be used to delivery mRNA to mouse muscle and nasal mucosa as well as ferret lungs .
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Cat. No.: HY-176512
CAS No.: 3100308-37-7
Target:  

Liposome

Research Areas:  

Others

FO-32 is an ionizable lipid and mRNA delivery carrier with state-of-the-art aerosolized mRNA delivery capability. FO-32 delivers mRNA to mouse muscle, nasal mucosa, lung, as well as ferret lung epithelium (including conducting airways). FO-32 can be used in studies related to the generation of lipid nanoparticles (LNPs) and the optimization of drug delivery .
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Cat. No.: HY-78086R
CAS No.: 620-23-5
Synonyms: 3-Methylbenzaldehyde (Standard)
m-Tolualdehyde (Standard) is the analytical standard of m-Tolualdehyde (HY-78086). This product is intended for research and analytical applications. m-Tolualdehyde (3-Methylbenzaldehyde) is an aldehyde metabolite produced by m-xylene metabolism, and it bidirectionally regulates the CYP 2B1, CYP 2E1, and CYP 4B1 isoenzymes in the respiratory tract of rats. m-Tolualdehyde serves as an oxidation substrate and carbon source for Pseudomonas Pxy, and it can be oxidized to m-toluic acid in an NAD + -dependent manner. m-Tolualdehyde exerts a dose-dependent inhibitory effect on CYP 2B1 and CYP 2E1 in the nasal mucosa and lungs of rats, and a dose-dependent activating effect on pulmonary CYP 4B1. m-Tolualdehyde can form aldehyde-heme adducts with the heme group of cytochrome P450. m-Tolualdehyde can be used in studies related to metabolic enzymes in the respiratory tract of rats .
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Cat. No.: HY-105025B
CAS No.: 85503-03-3
Synonyms: Thymopoietin II (32-35) acetate; TP 4 acetate
Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology

Thymocartin (TP 4) acetate is the 32-35 fragment of thymic factor (thymopoietin). Thymocartin acetate inhibits apoptosis of peripheral blood lymphocytes in HIV infected individuals. Thymocartin acetate is potential for immunodeficiency diseases research .
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