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Results for "

nasal mucosa

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (2) Apoptosis (1) CGRP Receptor (1) Endogenous Metabolite (1) Liposome (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (3) Inflammation/Immunology (3)
Oligonucleotides:	Cationic Lipids (1)

Inhibitors & Agonists

Peptides

Oligonucleotides

Targets Recommended: MALT1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P1014

HCGRP-(8-37) 2 Publications Verification Human α-CGRP (8-37)	CGRP Receptor	Cardiovascular Disease
HCGRP-(8-37) (Human α-CGRP (8-37)) is a fragment of human calcitonin gene-related peptide (hCGRP) and an antagonist of the CGRP receptor, with an IC₅₀ of 32.1 pM against the CGRP receptor. HCGRP-(8-37) blocks adenylate cyclase activation induced by CGRP receptor ligands and attenuates vascular responses triggered by CGRP. HCGRP-(8-37) reduces capsaicin-induced vasodilation in porcine nasal mucosa and superficial skin. HCGRP-(8-37) serves as a research tool to distinguish effects mediated by CGRP or calcitonin receptors, and to investigate CGRP-induced vascular effects .

HY-116953

Lipoxin B4 LXB4	Endogenous Metabolite	Inflammation/Immunology
Lipoxin B4 (LXB4) is a structurally distinct product of arachidonic acid metabolism. Lipoxin B4 reduces leukocyte infiltration and mucus secretion in the nasal mucosa and decreases mast cell and eosinophil degranulation in the upper airway. Lipoxin B4 decreases airway inflammation, mucus metaplasia and hyper- responsiveness in the lower airway. Lipoxin B4 shows mucosal protective actions and has the potential for the research of allergic inflammation in the upper and lower airways .

HY-W015593

Methylhexanamine hydrochloride	Adrenergic Receptor	Cardiovascular Disease
Methylhexanamine hydrochloride is an aliphatic amine and a vasoconstrictor that can be administered by inhalation to the nasal mucosa to exert its effect as a nasal decongestant .

HY-171948

FO-35	Liposome	Cancer
FO-35 is an ionizable lipid that can be used to synthesize lipid nanoparticles (LNPs). FO-35 can be used to delivery mRNA to mouse muscle and nasal mucosa as well as ferret lungs .

HY-12709A

ARC 239 dihydrochloride 1 Publications Verification	Adrenergic Receptor	Cardiovascular Disease Inflammation/Immunology
ARC 239 dihydrochloride is a selective α2B/2C adrenoceptor antagonist (pK_d values are 5.95, 7.41 and 7.56 at α2A, α2B, and α2C receptors respectively). ARC 239 dihydrochloride binds to CHO cell membranes expressing human recombinant a2A-, a2B- or a2C-adrenoceptor subtypes with pK_is of 5.6, 8.4, and 7.08, respectively .

HY-105025B

Thymocartin acetate Thymopoietin II (32-35) acetate; TP 4 acetate	Apoptosis	Inflammation/Immunology
Thymocartin (TP 4) acetate is the 32-35 fragment of thymic factor (thymopoietin). Thymocartin acetate inhibits apoptosis of peripheral blood lymphocytes in HIV infected individuals. Thymocartin acetate is potential for immunodeficiency diseases research .

Cat. No.	Product Name	Target	Research Area

HY-P1014

HCGRP-(8-37) 2 Publications Verification Human α-CGRP (8-37)	CGRP Receptor	Cardiovascular Disease
HCGRP-(8-37) (Human α-CGRP (8-37)) is a fragment of human calcitonin gene-related peptide (hCGRP) and an antagonist of the CGRP receptor, with an IC₅₀ of 32.1 pM against the CGRP receptor. HCGRP-(8-37) blocks adenylate cyclase activation induced by CGRP receptor ligands and attenuates vascular responses triggered by CGRP. HCGRP-(8-37) reduces capsaicin-induced vasodilation in porcine nasal mucosa and superficial skin. HCGRP-(8-37) serves as a research tool to distinguish effects mediated by CGRP or calcitonin receptors, and to investigate CGRP-induced vascular effects .

Cat. No.	Product Name		Classification

HY-171948

FO-35		Cationic Lipids
FO-35 is an ionizable lipid that can be used to synthesize lipid nanoparticles (LNPs). FO-35 can be used to delivery mRNA to mouse muscle and nasal mucosa as well as ferret lungs .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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