Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
nonmevalonate biosynthesis pathway
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "nonmevalonate biosynthesis pathway" in MCE Product Catalog:
Synonyms: (E)-4-Hydroxy-3-methyl-but-2-enyl diphosphate lithium
Category:
Cat. No.: HY-151965
CAS No.: 3037689-82-7
Antimalarial agent 18 is an potent antimalarial agent, based on electronic, highly lipophilic and siderophoric properties. Antimalarial agent 18 belongs to acyloxymethyl series, as a fosmidomycin surrogate, which is potent IspC inhibitor against the non-mevalonate isoprenoid biosynthesis pathway. Antimalarial agent 18 inhibits P. falciparum (IC50=50 nM) and A. baumanii (IC50=390 nM) .
Cat. No.: HY-158335
DXR-IN-1 (Compound 13E) is an inhibitor of 1-deoxy-D-ketose 5-phosphate reductoisomerase (DXR). DXR-IN-1 is highly selective for P. falciparum DXR (IC50=0.030 μM). DXR-IN-1 inhibits the growth of P. falciparum by binding to the active site of DXR and blocking its catalytic activity .
Cat. No.: HY-E71489
Target:
Research Areas:
2-C-Methyl-D-erythritol 2,4-cyclodiphosphate synthase (EC 4.6.1.12) requires Mg2+ or Mn2+ for its catalytic activity and is part of the non-mevalonate pathway for terpenoid biosynthesis.
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
