2 Results for "

pGC-B

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "pGC-B" in MCE Product Catalog:

Cat. No.: HY-P3624
CAS No.: 507289-11-4
Target:  

Guanylate Cyclase

Research Areas:  

Cardiovascular Disease

Cenderitide is a potent agonist of particulate guanylyl cyclase receptor (pGC). Cenderitide is a natriuretic peptide (NP) composed of C-type natriuretic peptide (CNP) fused to the C-terminus of Dendroaspis natriuretic peptide (DNP). Cenderitide activates both pGC-A and pGC-B, activates the second messenger cGMP, suppresses aldosterone, and preserves GFR without reducing blood pressure. Cenderitide can be used for heart failure research .
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Cat. No.: HY-P10720
CAS No.: 129405-72-7
Target:  

Endogenous Metabolite

Research Areas:  

Cardiovascular Disease

C-Type Natriuretic Peptide (1-53), Porcine, Rat, mouse is an activator of particulate guanylate cyclase B (pGC-B), which is highly expressed in endothelial cells, kidneys, and the heart. C-Type Natriuretic Peptide (1-53), Porcine, Rat, mouse can mediate a potent anti-fibrotic effect in human cardiac and renal fibroblasts by generating the second messenger cGMP .
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