98 Results for "

postoperative

" in MedChemExpress (MCE) Product Catalog:
Products (98)

98 Results for "postoperative" in MCE Product Catalog:

45
45 Publications Verification
Cat. No.: HY-P0264
CAS No.: 133514-43-9
Synonyms: Avexitide
Target:  

GLP Receptor

Research Areas:  

Metabolic Disease

Exendin(9-39) amide (Avexitide) is a glucagon-like peptide-1 (GLP-1) antagonist that competes with endogenous GLP-1 for binding to GLP-1 receptors, thereby antagonizing the effects of excess GLP-1 secretion. Exendin(9-39) amide can be used to study postoperative hypoglycemia (PBH) .
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22
22 Cited Publications
Cat. No.: HY-W010892
CAS No.: 6533-68-2
Synonyms: Hyoscine hydrobromide trihydrate
Scopolamine (Hyoscine) hydrobromide trihydrate is a high-affinity muscarinic antagonist that can cross the blood-brain barrier. Scopolamine hydrobromide trihydrate competitively antagonizes 5-HT3 receptors with an IC50 of 2.09 μM. Scopolamine hydrobromide trihydrate can induce cognitive and memory deficits in animals. Scopolamine hydrobromide trihydrate can be used in the research of preventing postoperative nausea and vomiting, motion sickness, nervous system diseases, etc .
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22
22 Cited Publications
Cat. No.: HY-B2065
CAS No.: 55-16-3
Synonyms: (-)-Scopolamine hydrochloride; Hyoscine hydrochloride
Scopolamine (Hyoscine) hydrochloride is a high-affinity muscarinic antagonist that can cross the blood-brain barrier. Scopolamine hydrochloride competitively antagonizes 5-HT3 receptors with an IC50 of 2.09 μM. Scopolamine hydrochloride can induce cognitive and memory deficits in animals. Scopolamine hydrochloride can be used in the research of preventing postoperative nausea and vomiting, motion sickness, nervous system diseases, etc .
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13
13 Cited Publications
Cat. No.: HY-B1892
CAS No.: 25953-19-9
Synonyms: Cephazolin
Cefazolin (Cephazolin) is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research . Cefazolin has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD) .
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13
13 Cited Publications
Cat. No.: HY-B1078
CAS No.: 27164-46-1
Synonyms: Cephazolin sodium
Cefazolin sodium is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research . Cefazolin sodium has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD) .
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11
11 Cited Publications
Cat. No.: HY-B0402
CAS No.: 768-94-5
Synonyms: 1-Adamantanamine; 1-Aminoadamantane
Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .
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11
11 Cited Publications
Cat. No.: HY-B0402A
CAS No.: 665-66-7
Synonyms: 1-Adamantanamine hydrochloride; 1-Adamantylamine hydrochloride; 1-Aminoadamantane hydrochloride
Amantadine (1-Adamantanamine) hydrochloride is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine hydrochloride inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine hydrochloride also has anti-orthopoxvirus and anticancer activity. Amantadine hydrochloride can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .
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10
10 Cited Publications
Cat. No.: HY-Y1889A
CAS No.: 9004-32-4
Synonyms: CMC-Na (MW 250000); CMC-Na (Viscosity:1500-3100 mPa.s)
Sodium carboxymethyl cellulose (CMC-Na) (MW 250000) is a sodium salt of carboxymethyl cellulose. Sodium carboxymethyl cellulose has adsorption and corrosion inhibition on low-carbon steel in an acidic medium. Sodium carboxymethyl cellulose can be used as a thickener, paste and barrier agent .
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5
5 Cited Publications
Cat. No.: HY-17474
CAS No.: 198470-84-7
Synonyms: SC 69124
Parecoxib (SC 69124) is a highly selective and orally active COX-2 inhibitor that is permeable to the blood-brain barrier, the proagent of Valdecoxib (HY-15762). Parecoxib Sodium is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits prostaglandin (PG) synthesis. Parecoxib can be used for the relief of acute postoperative pain and symptoms of chronic inflammatory conditions such as osteoarthritis and rheumatoid arthritis in vivo.
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5
5 Cited Publications
Cat. No.: HY-17474A
CAS No.: 198470-85-8
Synonyms: SC 69124A
Parecoxib Sodium (SC 69124A) is a highly selective and orally active COX-2 inhibitor that is permeable to the blood-brain barrier, the proagent of Valdecoxib (HY-15762). Parecoxib Sodium is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits prostaglandin (PG) synthesis. Parecoxib Sodium can be used for the relief of acute postoperative pain and symptoms of chronic inflammatory conditions such as osteoarthritis and rheumatoid arthritis in vivo.
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3
3 Cited Publications
Cat. No.: HY-B0406A
CAS No.: 590-63-6
Synonyms: Carbamyl-β-methylcholine chloride
Target:  

mAChR

Research Areas:  

Neurological Disease Cancer

Bethanechol chloride (Carbamyl-β-methylcholine chloride), a parasympathomimetic agent, is a mAChR agonist that exerts its effects via directly stimulating the mAChR (M1, M2, M3, M4, and M5) of the parasympathetic nervous system .
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3
3 Cited Publications
Cat. No.: HY-B0580
CAS No.: 74103-06-3
Synonyms: RS37619
Target:  

COX Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

Ketorolac (RS37619) is a non-steroidal anti-inflammatory drug (NSAID), acting as a nonselective COX inhibitor, with IC50s of 20 nM for COX-1 and 120 nM for COX-2. Ketorolac tromethamine is used as 0.5% ophthalmic solution for the research of allergic conjunctivitis, cystoid macular edema, intraoperative miosis, and postoperative ocular inflammation and pain. Ketorolac tromethamine is also a DDX3 inhibitor that can be used for cancer research .
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3
3 Cited Publications
Cat. No.: HY-B1164
CAS No.: 4093-35-0
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

Bromopride is a selective, irreversible, competitive, and orally effective dopamine D2 receptor antagonist. Bromopride can pass through the blood-brain barrier, inhibit the vomiting center, and enhance gastrointestinal motility, exerting antiemetic and gastrointestinal motility effects. Bromopride antagonizes dopamine-mediated vomiting reflexes and promotes gastrointestinal smooth muscle contraction, and has no adverse effects on abdominal wall healing in rats with postoperative abdominal infection. Bromopride can be used for the study of digestive system diseases (such as gastric hypomotility, nausea and vomiting) .
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2
2 Cited Publications
Cat. No.: HY-13243
CAS No.: 156053-89-3
Purity:  98.66%
Synonyms: ADL 8-2698; LY 246736
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

Alvimopan (ADL 8-2698) is a potent, selective, orally active and reversible μ-opioid receptor antagonist, with an IC50 of 1.7 nM. Alvimopan has selectivity for μ-opioid receptor (Ki=0.47 nM) over κ- and δ-opioid receptors (Kis=100, 12 nM, respectively). Alvimopan can be used for the research of postoperative ileus .
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2
2 Cited Publications
Cat. No.: HY-107802
CAS No.: 116122-36-2
Purity:  95.59%
Synonyms: Breviscapinun
Breviscapine (Breviscapinun) is a flavonoid compound with antioxidant, anti-inflammatory, anti-fibrotic, and neuroprotective activities. Breviscapine ameliorates cerebral ischemia/reperfusion injury and vascular dementia, and inhibits the formation of postoperative abdominal adhesions. The mechanism of action of Breviscapine involves the regulation of oxidative stress, inflammatory cytokines, signaling pathways such as TGF-β/Smad, and cellular calcium overload. Breviscapine is used for research on diseases including cardiovascular and cerebrovascular diseases .
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2
2 Cited Publications
Cat. No.: HY-76657A
CAS No.: 170098-38-1
Synonyms: ADL 8-2698 dihydrate; LY 246736 dihydrate
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease Cancer

Alvimopan dihydrate (ADL 8-2698 dihydrate) is a potent, selective, orally active and reversible μ-opioid receptor antagonist, with an IC50 of 1.7 nM. Alvimopan dihydrate has selectivity for μ-opioid receptor (Ki=0.47 nM) over κ- and δ-opioid receptors (Kis=100, 12 nM, respectively). Alvimopan dihydrate can be used for the research of postoperative ileus .
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1
1 Cited Publications
Cat. No.: HY-B1206
CAS No.: 51-60-5
Target:  

Cholinesterase (ChE)

Research Areas:  

Infection Neurological Disease

Neostigmine methyl sulfate is an AchE inhibitor. Neostigmine methyl sulfate increases endogenous acetylcholine levels, mediates antinociceptive effects, and alleviates heat-induced pain. Neostigmine methyl sulfate can be used in studies related to postoperative pain and sepsis .
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1
1 Cited Publications
Cat. No.: HY-B1924
CAS No.: 213997-73-0
Synonyms: N-Demethylvancomycin monohydrochloride; NVCM monohydrochloride
Target:  

Bacterial

Research Areas:  

Infection

Norvancomycin hydrochloride is a cell wall synthesis inhibitor targeting peptidoglycan precursors of Gram-positive bacteria and cannot pass the blood-brain barrier. Norvancomycin hydrochloride can competitively bind to peptidoglycan precursors, irreversibly inhibit bacterial cell wall synthesis, and exert antibacterial activity. Norvancomycin hydrochloride is mainly used in the study of Gram-positive bacterial infections, especially infections caused by methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Staphylococcus epidermidis (MRSE). Norvancomycin hydrochloride can also be incorporated into the bionic calcium phosphate coating of titanium implants to enhance antibacterial activity and inhibit postoperative orthopedic infections .
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1
1 Cited Publications
Cat. No.: HY-B0580C
CAS No.: 167105-81-9
Synonyms: RS37619 hemicalcium
Target:  

COX Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

Ketorolac (RS37619) hemicalcium is a non-steroidal anti-inflammatory drug (NSAID), acting as a nonselective COX inhibitor, with IC50s of 20 nM for COX-1 and 120 nM for COX-2. Ketorolac tromethamine is used as 0.5% ophthalmic solution for the research of allergic conjunctivitis, cystoid macular edema, intraoperative miosis, and postoperative ocular inflammation and pain. Ketorola chemicalcium is also a DDX3 inhibitor that can be used for cancer research .
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Cat. No.: HY-13102
CAS No.: 348622-88-8
Purity:  99.92%
Research Areas:  

Others

UK-383367 is an orally available pro-collagen C-protease inhibitor (BMP-1) with an IC50 value of 44 nM. UK-383367 can reduce renal fibrosis and inflammation in chronic kidney disease (CKD) and may be used to study postoperative skin scarring .
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