4093-35-0
Chemical Structure
Bromopride
- CAS No.: 4093-35-0
- Formula:C14H22BrN3O2
- Molecular Weight:344.25
IUPAC Name: 4-amino-5-bromo-N-(2-(diethylamino)ethyl)-2-methoxybenzamide
InChIKey: GIYAQDDTCWHPPL-UHFFFAOYSA-N
SMILES: O=C(NCCN(CC)CC)C1=CC(Br)=C(N)C=C1OC
Biological Activity: Bromopride is a selective, irreversible, competitive, and orally effective dopamine D2 receptor antagonist. Bromopride can pass through the blood-brain barrier, inhibit the vomiting center, and enhance gastrointestinal motility, exerting antiemetic and gastrointestinal motility effects. Bromopride antagonizes dopamine-mediated vomiting reflexes and promotes gastrointestinal smooth muscle contraction, and has no adverse effects on abdominal wall healing in rats with postoperative abdominal infection. Bromopride can be used for the study of digestive system diseases (such as gastric hypomotility, nausea and vomiting)[1][2].
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Bromopride | 99.53% | Bromopride is a selective, irreversible, competitive, and orally effective dopamine D2 receptor antagonist. Bromopride can pass through the blood-brain barrier, inhibit the vomiting center, and enhance gastrointestinal motility, exerting antiemetic and gastrointestinal motility effects. Bromopride antagonizes dopamine-mediated vomiting reflexes and promotes gastrointestinal smooth muscle contraction, and has no adverse effects on abdominal wall healing in rats with postoperative abdominal infection. Bromopride can be used for the study of digestive system diseases (such as gastric hypomotility, nausea and vomiting). | ||||||||||||||||||||
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Keywords
