51-60-5
51-60-5
Chemical Structure
Neostigmine (methyl sulfate)
- CAS No.: 51-60-5
- Formula:C13H22N2O6S
- Molecular Weight:334.39
IUPAC Name: 3-((dimethylcarbamoyl)oxy)-N,N,N-trimethylbenzenaminium methyl sulfate
InChIKey: OSZNNLWOYWAHSS-UHFFFAOYSA-M
SMILES: C[N+](C)(C)C1=CC=CC(OC(N(C)C)=O)=C1.O=S(OC)([O-])=O
Biological Activity: Neostigmine methyl sulfate is an AchE inhibitor. Neostigmine methyl sulfate increases endogenous acetylcholine levels, mediates antinociceptive effects, and alleviates heat-induced pain. Neostigmine methyl sulfate can be used in studies related to postoperative pain and sepsis[1][2][3].
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Neostigmine (methyl sulfate) | 99.50% | Neostigmine methyl sulfate is an AchE inhibitor. Neostigmine methyl sulfate increases endogenous acetylcholine levels, mediates antinociceptive effects, and alleviates heat-induced pain. Neostigmine methyl sulfate can be used in studies related to postoperative pain and sepsis. | ||||||||||||||||||||
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Neostigmine (methyl sulfate) (Standard) | 98.94% | Neostigmine (methyl sulfate) (Standard) is the analytical standard of Neostigmine (methyl sulfate). This product is intended for research and analytical applications. 0 | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.85
HY-119792ANeostigmine hydroxide -
Similarity Score 0.85
HY-126175Neostigmine iodide -
Similarity Score 0.85
HY-B0423RNeostigmine Bromide (Standard) -
Similarity Score 0.66
HY-W548400Rivastigmine impurity 3 -
Similarity Score 0.65
HY-133776Rivastigmine carbamate impurity -
Similarity Score 0.65
HY-121338RKarbutilate (Standard) -
Similarity Score 0.65
HY-W703245Rivastigmine impurity 8 -
Similarity Score 0.64
HY-146663AAChE/BChE-IN-3 hydrochloride -
Similarity Score 0.64
HY-146663AChE/BChE-IN-3 -
Explore the MedChemAI to find more analogs
References
- [1]. Buvanendran A, et al. Useful adjuvants for postoperative pain management. Best Pract Res Clin Anaesthesiol. 2007;21(1):31-49. [Content Brief]
- [2]. Rathna Prabha, et al. GENOTOXICITY OF BLOXIVERZ (NEOSTIGMINE METHYLSULFATE) ON BONE MARROW CELLS OF MOUSE. ejpmr, 2016,3(7), 263-269.
- [3]. Zabrodskii PF, et al. The Influence of Various Drags on Mortality of Mice and the Concentration of Proinflammatory Cytokines in Blood at Sepsis Caused by E. Coli. Adv Case Stud. 1(3).
