2. Disease Areas
  3. Neurological, Eye or Ear Disease
  4. Pain
  5. Postoperative Pain

Postoperative Pain

Postoperative pain is a common and expected consequence of surgical procedures, particularly those involving bone or extensive tissue manipulation, characterized by an acute increase in pain intensity during the early recovery phase. It is typically assessed using tools like the Visual Analog Scale (VAS) or morphine sulfate equivalent consumption and is influenced by factors including anesthesia type, surgical technique, and patient-specific variables. Pain often peaks within the first 2 to 5 days post-surgery and may persist longer in cases involving nonunion corrections or skin graft harvesting, where additional tissue trauma contributes to heightened discomfort. While generally temporary, postoperative pain can be significant and requires effective management to support recovery and prevent chronicity.

Postoperative Pain (6):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B0890
    Zomepirac sodium salt 64092-48-4 99.63%
    Zomepirac sodium salt (McN-2783-21-98) is an orally active prostaglandin synthetase inhibitor. Zomepirac sodium salt blocks prostaglandin synthesis and inhibits Collagen (HY-P72147)- or Epinephrine (HY-B0447)-induced platelet aggregation. Zomepirac sodium salt can be used for the research of postoperative pain and osteoarthritis.
    Zomepirac sodium salt
  • HY-W145486
    Calcium gluconate 299-28-5 99.86%
    Calcium gluconate is an orally effective calcium salt supplement. Calcium gluconate reduces elevated serum potassium, decreased serum calcium, and postoperative myalgia associated with succinylcholine administration. Calcium gluconate restores calcium homeostasis, skeletal integrity, bone mineralization and bone density, and maintains levels of parathyroid hormone, bone resorption markers and osteoclasts. Calcium gluconate reverses LPS (HY-D1056)-induced ERK phosphorylation, inflammatory cytokine release and acute lung injury, alleviates airway inflammatory damage and suppresses immune responses. Calcium gluconate can be used in research related to postoperative myalgia, osteoporosis/osteomalacia and acute lung injury.
    Calcium gluconate
  • HY-164795
    SBI-810 1849603-79-7 98.25%
    SBI-810 is a blood-brain barrier-permeable NTSR1 modulator. SBI-810 promotes the recruitment of β-arrestin-2 to NTSR1 and antagonizes NTSR1-mediated Gq activation. SBI-810 inhibits excitatory synaptic transmission, NMDA receptor and extracellular signal-regulated kinase (ERK) signaling in spinal nociceptive neurons, reduces surface expression of Nav1.7 and action potential firing in primary sensory neurons, and attenuates C-fiber responses. SBI-810 effectively alleviates acute and chronic pain in various rodent models through peripheral and central modulation. SBI-810 is applicable to research related to multiple pain disorders.
    SBI-810
  • HY-164795A
    SBI-810 hydrochloride 2772746-58-2 99.55%
    SBI-810 hydrochloride is a blood-brain barrier-permeable NTSR1 modulator. SBI-810 hydrochloride promotes the recruitment of β-arrestin-2 to NTSR1 and antagonizes NTSR1-mediated Gq activation. SBI-810 hydrochloride inhibits excitatory synaptic transmission, NMDA receptor and extracellular signal-regulated kinase (ERK) signaling in spinal nociceptive neurons, reduces surface expression of Nav1.7 and action potential firing in primary sensory neurons, and attenuates C-fiber responses. SBI-810 hydrochloride effectively alleviates acute and chronic pain in various rodent models through peripheral and central modulation. SBI-810 hydrochloride is applicable to research related to multiple pain disorders.
    SBI-810 hydrochloride
  • HY-B0890A
    Zomepirac 33369-31-2
    Zomepirac (McN-2783-21-98 free acid) is an orally active prostaglandin synthetase inhibitor. Zomepirac blocks prostaglandin synthesis and inhibits Collagen (HY-P72147)- or Epinephrine (HY-B0447)-induced platelet aggregation. Zomepirac can be used for the research of postoperative pain and osteoarthritis.
    Zomepirac
  • HY-B0890R
    Zomepirac sodium salt (Standard) 64092-48-4
    Zomepirac sodium salt (Standard) is the analytical standard of Zomepirac sodium salt (HY-B0890). This product is intended for research and analytical applications. Zomepirac sodium salt (McN-2783-21-98) is an orally active prostaglandin synthetase inhibitor. Zomepirac sodium salt blocks prostaglandin synthesis and inhibits Collagen (HY-P72147)- or Epinephrine (HY-B0447)-induced platelet aggregation. Zomepirac sodium salt can be used for the research of postoperative pain and osteoarthritis.
    Zomepirac sodium salt (Standard)