64092-48-4
64092-48-4
Chemical Structure
Zomepirac sodium salt
Synonym(s): McN-2783-21-98
- CAS. Nr.: 64092-48-4
- Formula:C15H13ClNNaO3
- Molecular Weight:313.71
IUPAC Name: sodium 2-(5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrol-2-yl)acetate
InChIKey: SEEXPXUCHVGZGU-UHFFFAOYSA-M
SMILES: O=C(O[Na])CC1=CC(C)=C(C(C2=CC=C(Cl)C=C2)=O)N1C
Biological Activity: Zomepirac sodium salt (McN-2783-21-98) is an orally active prostaglandin synthetase inhibitor. Zomepirac sodium salt blocks prostaglandin synthesis and inhibits Collagen (HY-P72147)- or Epinephrine (HY-B0447)-induced platelet aggregation. Zomepirac sodium salt can be used for the research of postoperative pain and osteoarthritis[1][2][3][4].
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Zomepirac sodium salt | 99.63% | Zomepirac sodium salt (McN-2783-21-98) is an orally active prostaglandin synthetase inhibitor. Zomepirac sodium salt blocks prostaglandin synthesis and inhibits Collagen (HY-P72147)- or Epinephrine (HY-B0447)-induced platelet aggregation. Zomepirac sodium salt can be used for the research of postoperative pain and osteoarthritis. | ||||||||||||||||||||
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Zomepirac sodium salt (Standard) | ≥98% | Zomepirac sodium salt (Standard) is the analytical standard of Zomepirac sodium salt (HY-B0890). This product is intended for research and analytical applications. Zomepirac sodium salt (McN-2783-21-98) is an orally active prostaglandin synthetase inhibitor. Zomepirac sodium salt blocks prostaglandin synthesis and inhibits Collagen (HY-P72147)- or Epinephrine (HY-B0447)-induced platelet aggregation. Zomepirac sodium salt can be used for the research of postoperative pain and osteoarthritis. | ||||||||||||||||||||
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References
- [1]. Lewis JR. Zomepirac sodium. A new nonaddicting analgesic. JAMA. 1981 Jul 24-31;246(4):377-9. [Content Brief]
- [2]. Smith PC, et al. Irreversible binding of zomepirac to plasma protein in vitro and in vivo. J Clin Invest. 1986;77(3):934-939. [Content Brief]
- [3]. Morley PA, et al. Zomepirac: a review of its pharmacological properties and analgesic efficacy. Drugs. 1982;23(4):250-275. [Content Brief]
- [4]. Strom BL, et al. The effect of indication on hypersensitivity reactions associated with zomepirac sodium and other nonsteroidal antiinflammatory drugs. Arthritis Rheum. 1987;30(10):1142-1148. [Content Brief]
