14 Results for "

prenylflavonoid

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "prenylflavonoid" in MCE Product Catalog:

11
Icaritin
Icaritin
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11 Cited Publications
Cat. No.: HY-N0678
CAS No.: 118525-40-9
Synonyms: Anhydroicaritin
Category:  

Flavonols Plants Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Phenols Polyphenols Epimedium brevicornu Maxim. Berberidaceae Disease Research Fields Cancer

Target:  

JAK Autophagy Apoptosis

Icaritin (Anhydroicaritin) is a prenylflavonoid derivative from Epimedium brevicornuMaxim. and potently inhibits proliferation of K562 cells (IC50 of 8 µM) and primary CML cells (IC50 of 13.4 µM for CML-CP and 18 µM for CML-BC). Icaritin can regulate MAPK/ERK/JNK and JAK2/STAT3 /AKT signalings, also enhances osteogenesis [3.
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Isoxanthohumol
Isoxanthohumol
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4 Cited Publications
Cat. No.: HY-N2584A
CAS No.: 521-48-2
Category:  

Infection Flavonoids Anti-aging Humulus lupulus L. Flavonones Plants Moraceae Disease Research Fields Cancer

Target:  

HSV Apoptosis Reactive Oxygen Species (ROS) Autophagy CMV Fungal Integrin S100 Protein

Isoxanthohumol is an orally active flavonoid compound. Isoxanthohumol has biological activities such as anti-tumor, anti-inflammatory, antioxidant, antiviral, antifungal, and inhibition of adipogenesis. Isoxanthohumol can induce apoptosis, autophagy, and migration of tumor cells. Isoxanthohumol is active against viruses such as HSV, BVDV, CMV, and Rhino. Isoxanthohumol can be used for the research of tumors, metabolic, and inflammatory diseases .
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Glycyrrhisoflavone
Glycyrrhisoflavone
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Cat. No.: HY-N3962
CAS No.: 116709-70-7
Category:  

Flavonoids Leguminosae Metabolic Disease Phenols Polyphenols Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Isoflavones

Target:  

Glycosidase

Glycyrrhisoflavone, an active prenylflavonoid, inhibits α-glucosidase .
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LS-BF1
LS-BF1
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Cat. No.: HY-P3350
CAS No.: 2892148-58-0
Target:  

Bacterial

Research Areas:  

Infection

LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].
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Bonannione A
Bonannione A
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Cat. No.: HY-124896
CAS No.: 97126-57-3
Synonyms: 6-Geranylnaringenin; Mimulone
Category:  

Paulownia tomentosa (Thunb.) Steud. Scrophulariaceae Plants

Target:  

Phosphatase Apoptosis Autophagy

Bonannione A (6-Geranylnaringenin; Mimulone), a prenylflavonoid, is an orally active and potent protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC50 of 14 µM. Bonannione A triggers caspase-dependent apoptosis. Bonannione A induces autophagy through p53-mediated AMPK/mTOR pathway. Bonannione A shows anti-inflammatory, antiradical and anti-cancer activity .
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Cyclomorusin
Cyclomorusin
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Cat. No.: HY-N3668
CAS No.: 62596-34-3
Synonyms: Cyclomorusin A; Cyclomulberrochromene
Category:  

Flavonoids Plants Moraceae Other Flavonoids Morus alba Linn.

Target:  

Others

Cyclomorusin (Cyclomorusin A; Cyclomulberrochromene) is a prenylflavonoid with antiplatelet activity. Cyclomorusin also inhibits markedly collagen-induced platelet aggregation .
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Icaritin (Standard)
Icaritin (Standard)
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Cat. No.: HY-N0678R
CAS No.: 118525-40-9
Synonyms: Anhydroicaritin (Standard)
Category:  

Flavonols Human Gut Microbiota Metabolites Flavonoids Phenols Polyphenols Epimedium brevicornu Maxim. Plants Berberidaceae Endogenous metabolite

Target:  

JAK Reference Standards Autophagy Apoptosis

Icaritin (Standard) is the analytical standard of Icaritin. This product is intended for research and analytical applications. Icaritin (Anhydroicaritin) is a prenylflavonoid derivative from Epimedium brevicornuMaxim. and potently inhibits proliferation of K562 cells (IC50 of 8 μM) and primary CML cells (IC50 of 13.4 μM for CML-CP and 18 μM for CML-BC). Icaritin can regulate MAPK/ERK/JNK and JAK2/STAT3 /AKT signalings, also enhances osteogenesis [3.
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Sutchuenmedin A
Sutchuenmedin A
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Cat. No.: HY-N6572
CAS No.: 1197194-31-2
Category:  

Epimedium sutchuenense Franch. Flavonols Flavonoids Monophenols Other Diseases Phenols Plants Berberidaceae Disease Research Fields

Target:  

Others

Sutchuenmedin A is a prenylflavonoid. Sutchuenmedin A is isolated from the 70% EtOH extract of Epimedium sutchuenense .
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Glycyrrhisoflavone (Standard)
Glycyrrhisoflavone (Standard)
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Cat. No.: HY-N3962R
CAS No.: 116709-70-7
Category:  

Flavonoids Leguminosae Phenols Polyphenols Plants Glycyrrhiza uralensis Fisch. Isoflavones

Target:  

Reference Standards Glycosidase

Glycyrrhisoflavone (Standard) is the analytical standard of Glycyrrhisoflavone. This product is intended for research and analytical applications. Glycyrrhisoflavone, an active prenylflavonoid, inhibits α-glucosidase .
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Isoxanthohumol (Standard)
Isoxanthohumol (Standard)
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Cat. No.: HY-N2584AR
CAS No.: 521-48-2
Category:  

Flavonoids Humulus lupulus L. Flavonones Plants Moraceae

Target:  

Reference Standards HSV Apoptosis Reactive Oxygen Species (ROS) Autophagy CMV Fungal Integrin S100 Protein

Isoxanthohumol (Standard) is the analytical standard of Isoxanthohumol (HY-N2584A). This product is intended for research and analytical applications. Isoxanthohumol is an orally active flavonoid compound. Isoxanthohumol has biological activities such as anti-tumor, anti-inflammatory, antioxidant, antiviral, antifungal, and inhibition of adipogenesis. Isoxanthohumol can induce apoptosis, autophagy, and migration of tumor cells. Isoxanthohumol is active against viruses such as HSV, BVDV, CMV, and Rhino. Isoxanthohumol can be used for the research of tumors, metabolic, and inflammatory diseases .
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8-Lavandulylkaempferol
8-Lavandulylkaempferol
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Cat. No.: HY-N2779
CAS No.: 883859-83-4
Category:  

Flavonoids Leguminosae Flavones Plants Sophora flavescens Aiton

Target:  

Others

8-Lavandulylkaempferol is a flavonoid that can be isolated from Sophora flaWescens. 8-Lavandulylkaempferol exhibits cytotoxic activity against the KB epidermoid carcinoma cell line with an IC50 of 15.1 μg/mL .
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6,8-Diprenylnaringenin
6,8-Diprenylnaringenin
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Cat. No.: HY-122416
CAS No.: 68236-11-3
Synonyms: Lonchocarpol A; Senegalensin
Category:  

Erythrinasenegalensis DC. Metabolic Disease Plants Moraceae Flavonoids Leguminosae Humulus lupulus L. Flavonones Phenols Polyphenols Disease Research Fields Cancer

Target:  

BCRP

6,8-Diprenylnaringenin (Lonchocarpol A; Senegalensin), a hop prenylflavonoid, is a inhibitor of breast cancer resistance protein (BCRP/ABCG2). 6,8-Diprenylnaringenin inhibits ABCG2-mediated efflux of Mitoxantrone, and 3H-Methotrexate transport (IC50=0.41 μM) in HEK293 cells. 6,8-Diprenylnaringenin exhibits some estrogenicity, but its potency is less than 1% of that of 8-Prenylnaringenin .
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Anhydroicaritin-3,7-di-O-glucuronide
Anhydroicaritin-3,7-di-O-glucuronide
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Cat. No.: HY-N19800
CAS No.: 1231899-06-1
Category:  

Flavonols Flavonoids Endogenous metabolite

Target:  

Drug Metabolite

Anhydroicaritin-3,7-di-O-glucuronide is a diglucuronide metabolite of icaritin. Anhydroicaritin-3,7-di-O-glucuronide is also a conjugated metabolite derived from prenylated flavonoids of the genus *Epimedium* in rats. In an in vitro microsomal system, Anhydroicaritin-3,7-di-O-glucuronide is mainly catalyzed by UGT1A1 and UGT1A8. Anhydroicaritin-3,7-di-O-glucuronide is generated via sequential glucuronidation at the 3-OH and 7-OH sites of icaritin, or via further conversion from monoglucuronides of icaritin .
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Epimedonin L
Epimedonin L
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Cat. No.: HY-N9672
CAS No.: 2215102-38-6
Category:  

Flavonoids Flavones Epimedium brevicornum Maxim. Plants Berberidaceae

Target:  

Drug Derivative

Epimedonin L is a natural flavonoid.
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