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Results for "

proteinases

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (2) Amino Acid Derivatives (2) Amyloid-β (1) Autophagy (1) Bacterial (3) Biochemical Assay Reagents (7) Cathepsin (8) Dengue Virus (1) Elastase (11) Endogenous Metabolite (6) Endonuclease (1) Environmental Pollutants (1) Factor Xa (4) FKBP (1) Flavivirus (1) Fluorescent Dye (3) G Protein-coupled Receptor Kinase (GRK) (1) Histone Methyltransferase (1) HIV (1) HIV Protease (1) HSV (3) Influenza Virus (2) Integrin (1) Interleukin Related (1) Isotope-Labeled Compounds (2) Kallikrein (1) MMP (1) Parasite (4) Protease Activated Receptor (PAR) (13) Proteasome (7) Proteasome Cap Targeting Chimeras (2) Reference Standards (3) SARS-CoV (9) Ser/Thr Protease (19) Virus Protease (3)
By Research Areas:	Cancer (10) Cardiovascular Disease (4) Infection (23) Inflammation/Immunology (29) Metabolic Disease (8) Neurological Disease (2)
Oligonucleotides:	Aptamers (1)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Targets Recommended: Proteolytic Enzyme

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-108717

Proteinase K Maximum Cited Publications 23 Publications Verification Protease K	Ser/Thr Protease	Others
Proteinase K (Protease K) is a nonspecific serine protease that is useful for general digestion of proteins. Proteinase K is active in the presence of SDS or urea and over a wide range of pH (4-12), salt concentrations, and temperatures. Proteinase K can be use for promoting methods of viral nucleic acid extraction, and detection .

HY-15282

E-64 Maximum Cited Publications 23 Publications Verification Proteinase inhibitor E 64	Cathepsin Autophagy Bacterial	Inflammation/Immunology Cancer
E-64 (Proteinase inhibitor E 64) is a potent irreversible inhibitor against general cysteine proteases with IC₅₀ of 9 nM for papain.

HY-E70076

Subtilisin, bacillus licheniformis Bacillopeptidaseb	Biochemical Assay Reagents	Others
Subtilisin (Compound proteinase) (EC 3.4.21.62) is a proteolytic enzyme, isolated from Bacillus licheniformis. Subtilisin (Compound proteinase) has catalytic activity in anhydrous dimethyl formamide. Subtilisin (Compound proteinase) can be used as a catalyst for easy coupling between sugars and amino acids .

HY-B0385

Gabexate mesylate 4 Publications Verification FOY	Proteasome Factor Xa	Inflammation/Immunology
Gabexate mesylate (FOY) is is a competitive and non-antigenic synthetic inhibitor of trypsin-like serine proteinases. Gabexate mesylate inhibits human thrombin, urokinase, plasmin, and Factor Xa with K_is of 0.97, 1.3, 1.6, and 8.5 μM, respectively. Gabexate mesylate binds to human and bovine tryptase with K_is of 3.4 nM and 18 μM, respectively. Gabexate mesylate exerts an anticoagulant effect on the clotting activity of thrombin and has anti-inflammatory effect by viainhibition of NF-κB, proinflammatory cytokines, and nitric oxide. Gabexate mesylate is used for pancreatitis and disseminated intravascular coagulation .

HY-B2228

Proteinase, Aspergillus oryzae 1 Publications Verification	Biochemical Assay Reagents	Cancer
Proteinase, Aspergillus oryzae is a serine protease that hydrolyzes peptide bonds in protein substrates, preferring alkaline conditions (optimal pH 10.5). It efficiently degrades casein, poly-L-glutamic acid, and poly-L-lysine, with activity irreversibly inhibited by diisopropylfluorophosphate (DFP) and potato inhibitor. This enzyme catalyzes proteolysis via serine residues in its active site, finding applications in food processing (e.g., soy sauce fermentation), detergents, and leather industries due to its high yield in solid-state fermentation and cost-effective production.

HY-P1309

PAR-4 Agonist Peptide, amide 2 Publications Verification PAR-4-AP; AY-NH2	Protease Activated Receptor (PAR)	Inflammation/Immunology
PAR-4 Agonist Peptide, amide (PAR-4-AP; AY-NH2) is a proteinase-activated receptor-4 (PAR-4) agonist, which has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist.

HY-E70194

Endoproteinase Glu-C (MS grade) V8 protease; Glu-C	Ser/Thr Protease	Others
Endoproteinase Glu-C (MS grade) is a serine proteinase. Endoproteinase GluC is able to hydrolyze some serpins and all classes of mammalian immunoglobulins .

HY-108137

Z-LVG-CHN2 2 Publications Verification	Cathepsin HSV SARS-CoV	Infection Inflammation/Immunology
Z-LVG-CHN2 is a cell-permeable and irreversible inhibitor of cysteine proteinase. Z-LVG-CHN2 is a tripeptide derivative and mimics part of the human cysteine proteinase-binding center. Z-LVG-CHN2 displays an inhibition on HSV whereas no significant effect on poliovirus replication. Z-LVG-CHN2 effectively blocks SARS-COV-2 replication (EC₅₀=190 nM) via inhibition of SARS-COV-2 3CL pro protease .

HY-D0817

Rhodamine 110 Rhodamine 110 chloride; RH110	Fluorescent Dye	Others
Rhodamine 110 is a sensitive and selective substrate for assaying proteinases in solution or inside living cells. The excitation wavelength is 498 nm and the emission wavelength is 521 nm .

HY-D0981

7-Amino-4-(trifluoromethyl)coumarin 1 Publications Verification Coumarin 151; AFC	Fluorescent Dye	Others
7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) is a fluorescent marker for the sensitive detection of proteinases. The excitation and emission wavelengths are 400 and 490 nm, respectively.

HY-103351

Cathepsin G Inhibitor I	Cathepsin	Inflammation/Immunology
Cathepsin G Inhibitor I (Compound 7) is a potent, selective, reversible, competitive, non-peptidic Cathepsin G inhibitor (IC₅₀ = 53 nM; K_i = 63 nM). Cathepsin G Inhibitor I can be used in research related to immune disorders .

HY-148826

Rovunaptabin ARC 183; BC 007	G Protein-coupled Receptor Kinase (GRK)	Cardiovascular Disease
Rovunaptabin (ARC 183) is an aptamer, a single-stranded DNA molecule composed of 15 deoxynucleotides. It acts as a broad-spectrum neutralizer of pathogenic G-protein-coupled receptor autoantibodies. Rovunaptabin can be used in research related to cardiomyopathy and pulmonary hypertension .

HY-P2661

FA-Leu-Gly-Pro-Ala-OH	Biochemical Assay Reagents Bacterial	Infection
FA-Leu-Gly-Pro-Ala-OH is a furylacryloyl-terminal tetrapeptide that serves as a substrate for bacterial collagenase and spirochete metalloendopeptidase. FA-Leu-Gly-Pro-Ala-OH is specifically hydrolyzed by spirochete collagenase only at the Leu-Gly bond. FA-Leu-Gly-Pro-Ala-OH can be used to determine the equilibrium constant of peptide bond hydrolysis, and also to detect collagenase-mediated cleavage reactions via turbidimetry based on absorbance reduction .

HY-108717B

Proteinase K (NGS grade) Protease K (NGS grade)	Ser/Thr Protease	Others
Proteinase K (Protease K) (NGS grade) is a nonspecific serine protease that is useful for general digestion of proteins. Proteinase K (NGS grade) is active in the presence of SDS or urea and over a wide range of pH (4-12), salt concentrations, and temperatures. Proteinase K (NGS grade) can be use for promoting methods of viral nucleic acid extraction, and detection. This product is NGS grade, no Nickase residue, and nucleic acid residue ≤5 pg/mg .

HY-P1314

2-Furoyl-LIGRLO-amide 2 Publications Verification	Protease Activated Receptor (PAR)	Inflammation/Immunology
2-Furoyl-LIGRLO-amide is a potent and selective proteinase-activated receptor 2 (PAR2) agonist with a pD₂ value of 7.0 ..

HY-19727A

FOY 251 2 Publications Verification	Ser/Thr Protease SARS-CoV	Metabolic Disease
FOY 251, an anti-proteolytic active metabolite Camostate (HY-13512), acts as a *proteinase* inhibitor . FOY 251 inhibits SARS-CoV-2 infection in cells assay .

HY-108717A

*Recombinant Proteinase* K (DNase & RNase free, animal free)** 2 Publications Verification Recombinant Protease K (DNase & RNase free, animal free)	Ser/Thr Protease	Others
Recombinant Proteinase K (Protease K) (DNase & RNase free, animal free) is a nonspecific serine protease that is useful for general digestion of proteins. Proteinase K (DNase & RNase free, animal free) is active in the presence of SDS or urea and over a wide range of pH (4-12), salt concentrations, and temperatures. Proteinase K (DNase & RNase free, animal free) can be use for promoting methods of viral nucleic acid extraction, and detection. This product is of molecular biology grade, free of animal-derived ingredients, and is recombinantly purified from yeast .

HY-15652

Freselestat ONO-6818; ONO-PO-736	Elastase	Inflammation/Immunology
Freselestat (ONO-6818) is a potent and orally active neutrophil elastase inhibitor with a K_i of 12.2 nM. Freselestat is >100-fold less-active against other proteases such as trypsin, protein-ase 3, pancreatic elastase, plasmin, thrombin, collagenase, cathepsin G, and murine macrophage elastase. Freselestat has a potent anti-inflammatory activity .

HY-114174

Fmoc-Ala-Glu-Asn-Lys-NH2 3 Publications Verification	Amyloid-β	Neurological Disease
Fmoc-Ala-Glu-Asn-Lys-NH2 is a selective asparagine endopeptidase (AEP) inhibitor peptide and suppresses amyloid precursor protein (APP) cleavage. AEP, a pH-controlled cysteine proteinase, is activated during ageing and mediates APP proteolytic processing .

HY-100943

Cinanserin hydrochloride 1 Publications Verification SQ 10643	5-HT Receptor Influenza Virus	Infection Inflammation/Immunology
Cinanserin hydrochloride (SQ 10643) is a potent, selective and highly affinity 5-HT₂ receptor antagonist with a K_i of 41 nM. Cinanserin hydrochloride has a much higher binding affinity for the 5-HT₂ than for the 5-HT₁ receptor (K_i of 3500 nM). Cinanserin is also an inhibitor of 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro .

HY-E70004

Microbial neutral proteinase	Biochemical Assay Reagents	Others
Microbial neutral proteinase is a neutral proteinase from microorganisms and is useful for cell isolation and tissue dissociation .

HY-136888

MeOSuc-AAPV-CMK Elastase Inhibitor III	Elastase Cathepsin	Others
MeOSuc-AAPV-CMK (Elastase Inhibitor III) is an elastase inhibitor. MeOSuc-AAPV-CMK also inhibits cathepsin G and proteinase 3.MeOSuc-AAPV-CMK blocks the cleavage of adiponectin by leukocyte elastase .

HY-121138

1,8-Dihydroxy-4,5-dinitroanthraquinone ARDP0006; DHDNE	Flavivirus Dengue Virus Virus Protease	Infection
1,8-Dihydroxy-4,5-dinitroanthraquinone (ARDP0006; DHDNE) is a potent inhibitor of *serine proteinase* NS2B/3*, the dengue viral protein. 1,8-Dihydroxy-4,5-dinitroanthraquinone has intermolecular proteinase* activity and viral inhibition ability with IC₅₀s of 432 μM and 4.2 μM, respectively. Meanwhile 1,8-Dihydroxy-4,5-dinitroanthraquinone inhibits NS2B/3 cleavage in BHK-21 cells at a dose ranging from 4.2 μM to 432 μM .

HY-155414

Neutrophil elastase inhibitor 5	Elastase	Inflammation/Immunology
Neutrophil elastase inhibitor 5 (compound 29) is a dual inhibitor of HNE (human neutrophil elastase) and proteinase 3 (PR3) with IC₅₀ values of 4.91 μM and 20.69 μM, respectively. Neutrophil elastase inhibitor 5 can be used in the study of neutrophil inflammatory diseases .

HY-P2518

Protease-Activated Receptor-1, PAR-1 Agonist	Protease Activated Receptor (PAR)	Inflammation/Immunology
Protease-Activated Receptor-1, PAR-1 Agonist is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist corresponds to PAR1 tethered ligand and which can selectively mimic theactions of thrombin via this receptor .

HY-P1309A

PAR-4 Agonist Peptide, amide TFA 2 Publications Verification PAR-4-AP TFA; AY-NH2 TFA	Protease Activated Receptor (PAR)	Inflammation/Immunology
PAR-4 Agonist Peptide, amide TFA (PAR-4-AP TFA; AY-NH2 TFA) is a proteinase-activated receptor-4 (PAR-4) agonist, which has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist .

HY-19269

FK706	Elastase	Inflammation/Immunology
FK706 is a potent, slow-binding and competitive inhibitor of human neutrophil elastase with an IC₅₀ of 83 nM and a K_i of 4.2 nM. FK706 also inhibits mouse neutrophil elastase and porcine pancreatic elastase with IC₅₀s of 22 nM and 100 nM, respectively, and has no inhibitory activity against other serine proteinases such as human pancreatic trypsin, human pancreatic α-chymotrypsin and human leukocyte cathepsin G. FK706 has anti-inflammatory effect .

HY-P0297

Protease-Activated Receptor-4	Protease Activated Receptor (PAR)	Others
Protease-Activated Receptor-4 is the agonist of proteinase-activated receptor-4 (PAR4).

HY-N16395

Jensenone	SARS-CoV Virus Protease	Infection
Jensenone is an acylphloroglucinol derivative. Jensenone binds to COVID-19 proteinase in molecular docking studies. Jensenone can be used as a COVID-19 Mpro inhibitor .

HY-34439

2,5-Dimethylpyrazine NSC 49139	Environmental Pollutants Endogenous Metabolite	Metabolic Disease
2,5-Dimethylpyrazine (NSC 49139) is an endogenous metabolite. 2,5-Dimethylpyrazine in produced in food systems of two whey protein hydrolysates, obtained using either trypsin or proteinase from Aspergillus melleus. 2,5-Dimethylpyrazine can be qualitatively monitored using a stable isotope dilution assay. 2,5-Dimethylpyrazine can also be generated via microbial mechanisms using Bacillus subtilis. 2,5-Dimethylpyrazine can be oxidized to form 5-methylpyrazine-2-carboxylic acid, which is the intermediate in the synthesis of antilipoltic agent. 2,5-Dimethylpyrazine is a volatile compound that can give a roasted peanut flavor .

HY-P5994

MeOSuc-AAPF-CMK MeOSuc-Ala-Ala-Pro-Phe-CH₂Cl	Ser/Thr Protease	Others
MeOSuc-AAPF-CMK (MeOSuc-Ala-Ala-Pro-Phe-CH Cl) is a potent proteinase K inhibitor .

HY-134910

SID-852843	Virus Protease	Infection
SID-852843 is a WNV NS2B-NS3 proteinase inhibitor. SID-852843 can inhibit WNV NS2B-NS3 proteinase activity with IC₅₀ value of 0.105 μM. SID-852843 can be used for the research of virus infection .

HY-122762

Cetraxate hydrochloride DV-1006	Ser/Thr Protease	Inflammation/Immunology
Cetraxate hydrochloride (DV-1006), an orally active anti-ulcer agent with mucosal protective effects, can be used for gastric ulcers research . Cetraxate hydrochloride is a potent *acrosomal proteinase* acrosin** inhibitor with a K_i and an IC₅₀ of 0.94 μM and 3.3 μM, respectively .

HY-P2922

Cathepsin C	Cathepsin	Cancer
Cathepsin C is a lysosomal cysteine protease essential for catalytic activation of many serine proteases, including proteinase 3 (PR3), neutrophil elastase (NE), cathepsin G (CTSG), granzyme A/B/C, and mast cell chymase .

HY-P3150

*Recombinant Proteinase* K**	Ser/Thr Protease	Others
Recombinant Proteinase K is a serine protease that cleaves the carboxy-terminated peptide bonds of aliphatic and aromatic amino acids. Recombinant Proteinase K can be used to digest proteins and remove contamination from nucleic acid preparations .

HY-131591

Digalacturonic acid	Endogenous Metabolite	Others
Digalacturonic acid is a metabolite of pectin or pectic acid. Digalacturonic acid can be used for the co-crystallization of enzymes such as proteinase K .

HY-163411

Neutrophil elastase inhibitor 6	Elastase	Inflammation/Immunology
Neutrophil elastase inhibitor 6 (compound 113) is an irreversible phosphonic-type inhibitor of human neutrophil elastase .

HY-114729

Leucylproline	Amino Acid Derivatives	Others
Leucylproline, a dipeptide, plays important roles in the medium-dependent regulation of proteinase activity .

HY-126809A

Bz-Pro-Phe-Arg-pNA hydrochloride Bz-PFR-pNA hydrochloride	Factor Xa	Others
Bz-Pro-Phe-Arg-pNA (Bz-PFR-pNA) hydrochloride is a chromogenic peptide substrate for plasma and glandular Kallikrein, cysteine proteinase (Cruzipain) and Trypsin. Bz-Pro-Phe-Arg-pNA hydrochloride can be used in Factor XII assay .

HY-P5459

Elafin(human)	Bacterial Elastase	Infection
Elafin,also known as elafin-specific inhibitor (ESI) or skin anti-leucoprotease (SKALP), is a low molecular weight inhibitor of human neutrophil elastase (HNE) and proteinase 3 in lung. Elafin is antibiotic against Pseudomonas aeruginosa and Staphylococcus aureus .

HY-19727

FOY 251 free base	Ser/Thr Protease SARS-CoV	Infection Metabolic Disease
FOY 251 free base, an anti-proteolytic active metabolite of Camostate (HY-13512), acts as a *proteinase* inhibitor . FOY 25 free base inhibits SARS-CoV-2 infection in cells assay .

HY-108137A

Z-L(D-Val)G-CHN2	Cathepsin HSV SARS-CoV	Infection
Z-L(D-Val)G-CHN2 is the isoform of Z-LVG-CHN2 (HY-108137). Z-LVG-CHN2 is a cell-permeable and irreversible inhibitor of cysteine proteinase. Z-LVG-CHN2 is a tripeptide derivative and mimics part of the human cysteine proteinase-binding center. Z-LVG-CHN2 displays an inhibition on HSV whereas no significant effect on poliovirus replication. Z-LVG-CHN2 effectively blocks SARS-COV-2 replication (EC₅₀=190 nM) via inhibition of SARS-COV-2 3CL pro protease .

HY-W013097

Boc-Arg(di-Z)-OH	Amino Acid Derivatives	Others
Boc-Arg(di-Z)-OH can be used for the synthesis of amino acid. Boc-Arg(di-Z)-OH can be used for the research of inhibitors for processing proteinases. Boc-Arg(di-Z)-OH is coupled via the mixed anhydride (MA) with HGlu(OBzl)-Lys(Z)-Arg(Z,Z)-CH2Cl .

HY-177910

Anticoronavirus agent-1	SARS-CoV	Infection
Anticoronavirus agent-1 (Compound IV-2) is a 1,4-naphthone compound and is a 3CL hydrolase inhibitor (3C-like proteinase) of the 19-nCoV novel coronavirus. Anticoronavirus agent-1 has low cytotoxity on HSF cells. Anticoronavirus agent-1 can be used for the study of the novel coronavirus .

HY-106448

Midesteine MR 889	Ser/Thr Protease	Inflammation/Immunology
Midesteine (MR 889) is a *proteinase* inhibitor that can inhibit porcine pancreatic elastase, human neutrophil elastase and bovine chymotrypsin. Midesteine has the potential for chronic obstructive pulmonary disease (COPD) and chronic bronchitis research .

HY-139697

*HAV 3C proteinase-IN-1*	Others	Infection
HAV 3C proteinase-IN-1 is a inhibitor of Hepatitis A virus 3C proteinase.

HY-105492

AG-1284	HIV Protease	Infection
AG-1284 is a HIV proteinase inhibitor with an EC₅₀ of 0.5 mg/mL. AG-1284 can be used for the research of infection .

HY-P1314A

2-Furoyl-LIGRLO-amide TFA	Protease Activated Receptor (PAR)	Inflammation/Immunology
2-Furoyl-LIGRLO-amide TFA is a potent and selective proteinase-activated receptor 2 (PAR2) agonist with a pD₂ value of 7.0 ..

HY-P1536

Thrombin Receptor Activator for Peptide 5 (TRAP-5)	Protease Activated Receptor (PAR)	Cardiovascular Disease
Thrombin Receptor Activator for Peptide 5 (TRAP-5) is also called Coagulation Factor II Receptor (1-5) or Proteinase Activated Receptor 1 (1-5), used in the research of coronary heart disease (CHD).

HY-119337

CE-2072	Ser/Thr Protease	Infection
CE-2072 is an inhibitor of serine proteases neutrophil elastase and *proteinase-3. CE-2072 inhibits HIV-1* production and p24 production in response to IL-18 or NaCl in infected U1 monocytic cells, reduces virus replication in infected peripheral blood mononuclear cells and blocks infection of permissive HeLa cells. CE-2072 suppresses activation of the HIV-1-inducing transcription factor NF-kB in U1 cells. CE-2072 is promising for research of HIV-1-related disease .

Cat. No.	Product Name

HY-L147

Protease Inhibitor Library

927 compounds

A protease (also called a peptidase, proteinase, or proteolytic enzyme) is an enzyme that catalyzes proteolysis, breaking down proteins into smaller polypeptides or single amino acids, and spurring the formation of new protein products. Proteases play important roles in regulating multiple biological processes in all living organisms, such as regulating the fate, localization, and activity of many proteins, modulating protein-protein interactions, creating new bioactive molecules, contributing to the processing of cellular information, and generating, transducing, and amplifying molecular signals.

Proteases are important targets in drug discovery. Some protease inhibitors are often used as anti-virus drugs and anti-cancer drugs. MCE offers a unique collection of 927 protease inhibitors. MCE Protease Inhibitor Library is critical for drug discovery and development.

Cat. No.	Product Name	Type

HY-D0817

Rhodamine 110 Rhodamine 110 chloride; RH110	Fluorescent Dyes
Rhodamine 110 is a sensitive and selective substrate for assaying proteinases in solution or inside living cells. The excitation wavelength is 498 nm and the emission wavelength is 521 nm .

HY-D0981

7-Amino-4-(trifluoromethyl)coumarin 1 Publications Verification Coumarin 151; AFC	Fluorescent Dyes
7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) is a fluorescent marker for the sensitive detection of proteinases. The excitation and emission wavelengths are 400 and 490 nm, respectively.

HY-D1532

DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS	Fluorescent Dyes
DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS is a fluorescent dye, and can be applied in a fluorogenic substrate for an aspartyl proteinase from human malaria parasite .

Cat. No.	Product Name	Type

HY-B2228

Proteinase, Aspergillus oryzae

1 Publications Verification

Biochemical Assay Reagents

Proteinase, Aspergillus oryzae is a serine protease that hydrolyzes peptide bonds in protein substrates, preferring alkaline conditions (optimal pH 10.5). It efficiently degrades casein, poly-L-glutamic acid, and poly-L-lysine, with activity irreversibly inhibited by diisopropylfluorophosphate (DFP) and potato inhibitor. This enzyme catalyzes proteolysis via serine residues in its active site, finding applications in food processing (e.g., soy sauce fermentation), detergents, and leather industries due to its high yield in solid-state fermentation and cost-effective production.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N16395

Jensenone	Phenols Polyphenols Myrtaceae Eucalyptus jensenii Maiden Plants Source Classification	SARS-CoV Virus Protease
Jensenone is an acylphloroglucinol derivative. Jensenone binds to COVID-19 proteinase in molecular docking studies. Jensenone can be used as a COVID-19 Mpro inhibitor .

HY-34439

2,5-Dimethylpyrazine NSC 49139	Structural Classification Natural Products Microorganisms Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Environmental Pollutants Endogenous Metabolite
2,5-Dimethylpyrazine (NSC 49139) is an endogenous metabolite. 2,5-Dimethylpyrazine in produced in food systems of two whey protein hydrolysates, obtained using either trypsin or proteinase from Aspergillus melleus. 2,5-Dimethylpyrazine can be qualitatively monitored using a stable isotope dilution assay. 2,5-Dimethylpyrazine can also be generated via microbial mechanisms using Bacillus subtilis. 2,5-Dimethylpyrazine can be oxidized to form 5-methylpyrazine-2-carboxylic acid, which is the intermediate in the synthesis of antilipoltic agent. 2,5-Dimethylpyrazine is a volatile compound that can give a roasted peanut flavor .

HY-131591

Digalacturonic acid	Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Digalacturonic acid is a metabolite of pectin or pectic acid. Digalacturonic acid can be used for the co-crystallization of enzymes such as proteinase K .

HY-N4332

Rivulariapeptolides 1121	Natural Products Microorganisms Source Classification	Ser/Thr Protease
Rivulariapeptolides 1121 is a high potent and selective serine protease inhibitor with IC₅₀ values of 35.52 nM, 13.24 nM and 48.05 nM for chymotrypsin, elastase and proteinase K, respectively .

HY-N4333

Rivulariapeptolides 988	Natural Products Microorganisms Source Classification	Ser/Thr Protease
Rivulariapeptolides 988 is a high potent and selective serine protease inhibitor with IC₅₀ values of 95.46 nM, 15.29 nM and 85.50 nM for chymotrypsin, elastase and proteinase K, respectively .

HY-N4331

Rivulariapeptolides 1185	Natural Products Microorganisms Source Classification	Ser/Thr Protease
Rivulariapeptolides 1185 is a high potent and selective serine protease inhibitor with IC₅₀ values of 13.17 nM, 23.59 nM and 55.26 nM for chymotrypsin, elastase and proteinase K, respectively .

Cat. No.	Product Name	Chemical Structure

HY-W654243

Isovalerylcarnitine-d9-1 chloride
Isovalerylcarnitine-d₉-1 (chloride) is deuterium labeled Isovalerylcarnitine (chloride). Isovalerylcarnitine chloride, a product of the catabolism of L-leucine, is a potent activator of the Ca ²⁺-dependent proteinase (calpain) of human neutrophils .

HY-W707562

FOY 251-d4
FOY 251-d₄ is the deuterium labeled FOY 251 (HY-19727A). FOY 251, an anti-proteolytic active metabolite Camostate (HY-13512), acts as a proteinase inhibitor . FOY 251 inhibits SARS-CoV-2 infection in cells assay .

Cat. No.	Product Name		Classification

HY-148826

Rovunaptabin ARC 183; BC 007		Aptamers
Rovunaptabin (ARC 183) is an aptamer, a single-stranded DNA molecule composed of 15 deoxynucleotides. It acts as a broad-spectrum neutralizer of pathogenic G-protein-coupled receptor autoantibodies. Rovunaptabin can be used in research related to cardiomyopathy and pulmonary hypertension .

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proteinases

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Oligonucleotides

Natural
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