1. Metabolic Enzyme/Protease
    Anti-infection
  2. Ser/Thr Protease
    SARS-CoV
  3. FOY 251

FOY 251 

Cat. No.: HY-19727A Purity: 98.01%
Handling Instructions

FOY 251 is an anti-proteolytic active metabolite camostate (HY-13512), acts as a proteinase inhibitor.FOY 251 inhibit SARS-CoV-2 infection in cells assay.

For research use only. We do not sell to patients.

FOY 251 Chemical Structure

FOY 251 Chemical Structure

CAS No. : 71079-09-9

Size Price Stock Quantity
5 mg USD 300 In-stock
Estimated Time of Arrival: December 31
10 mg USD 500 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

FOY 251 is an anti-proteolytic active metabolite camostate (HY-13512), acts as a proteinase inhibitor[1][2].FOY 251 inhibit SARS-CoV-2 infection in cells assay[1][3].

IC50 & Target

proteinase[1]

In Vitro

FOY-251 represents a dose-dependent inhibition of equivalent current in M-1 cells[2].
FOY-251 inhibits the proteolytic activity of prostasin[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

409.41

Formula

C₁₇H₁₉N₃O₇S

CAS No.

71079-09-9

SMILES

O=C(O)CC1=CC=C(OC(C2=CC=C(NC(N)=N)C=C2)=O)C=C1.CS(=O)(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 20 mg/mL (48.85 mM; ultrasonic and adjust pH to 5 with HCl)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4425 mL 12.2127 mL 24.4254 mL
5 mM 0.4885 mL 2.4425 mL 4.8851 mL
10 mM 0.2443 mL 1.2213 mL 2.4425 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: 2 mg/mL (4.89 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: 2 mg/mL (4.89 mM); Suspended solution; Need ultrasonic

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2 mg/mL (4.89 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

  • Dilution Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

FOY 251FOY251FOY-251Ser/Thr ProteaseSARS-CoVSerine proteasesSerine endopeptidasesThreonine proteasesSARS coronavirusproteolyticcamostateproteinasemetabolismobeseInhibitorinhibitorinhibit

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Product Name:
FOY 251
Cat. No.:
HY-19727A
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