2 Results for "

rat adrenal cortical microsomes

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "rat adrenal cortical microsomes" in MCE Product Catalog:

Cat. No.: HY-117876
CAS No.: 119256-78-9
Synonyms: CV 2961
Target:  

Angiotensin Receptor

Research Areas:  

Cardiovascular Disease

S 8308 (CV 2961) is a non-peptide angiotensin II (Angiotensin II receptor) receptor antagonist with transient oral activity and short-acting intravenous activity, and exhibits an IC50 of 15 μM in rats. S 8308 competitively blocks the binding of angiotensin II to its receptor, thereby inhibiting vasoconstriction and pressor responses. S 8308 can be used in the research of hypertension and renal hypertension .
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Cat. No.: HY-180401
CAS No.: 139964-19-5
Target:  

Angiotensin Receptor

Research Areas:  

Cardiovascular Disease

DMP 811 is a potent, orally active and selective angiotensin II subtype receptor AT1 antagonist. DMP 811 exhibits selectivity for AT1 (IC50 = 6 nM) over AT2 (IC50 >10 μM). DMP 811 exhibits potent antihypertensive activity in rats and dogs. DMP 811 can be used for the research of hypertension .
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