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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
receptor-gamma-t
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "receptor-gamma-t" in MCE Product Catalog:
Synonyms: BI 730357
Target:
Research Areas:
Bevurogant (BI 730357) is a retinoid-related orphan receptor-gamma t (RORγt) antagonist. Bevurogant can be used for the research of chronic inflammatory diseases .
Cat. No.: HY-W150866
CAS No.: 1083-27-8
Synonyms: Hexylparaben
Target:
Research Areas:
Hexyl 4-hydroxybenzoate (Hexylparaben) is a retinoic acid-related orphan receptor RORγ(t) agonist with an EC50 of 144 nM. Hexyl 4-hydroxybenzoate is used in the study of autoimmune diseases .
Target:
Research Areas:
S18-000003 is a potent, selective and orally active inhibitor of retinoic acid receptor-related orphan receptor-gamma-t (RORγt), with an IC50 of <30 nM towards human RORγt in competitive binding assays. S18-000003 shows selectivity for RORγt over other ROR family members (IC50>10 μM). S18-000003 can be used for the research of psoriasis with low risk of thymic aberrations .
Target:
Research Areas:
RORγt Inverse agonist 10 is a potent and orally bioavailable RORγt (retinoic acid receptor-related orphan nuclear receptor gamma t) inverse agonist, with an IC50 of 51 nM. RORγt is a major transcription factor of genes related to psoriasis pathogenesis such as IL-17A, IL-22, and IL-23R
Cat. No.: HY-112863
CAS No.: 1361413-10-6
Target:
Research Areas:
RORγt inhibitor 3 is an orally active and potent retinoic acid receptor-related orphan receptor-gamma-t (RORγt) inhibitor. RORγt inhibitor 3 shows high binding affinity and inhibitory activity of Th17 cell differentiation. RORγt inhibitor 3 also shows efficacy in both mouse experimental autoimmune encephalomyelitis (EAE) and collagen induced arthritis (CIA) models .
Cat. No.: HY-P83758
Synonyms: IMD42 antibody;
MGC129539 antibody;
NR1F3 antibody;
Nuclear receptor ROR gamma antibody;
Nuclear receptor subfamily 1 group F member 3 antibody;
RAR related orphan receptor C antibody;
Retinoic acid binding receptor gamma antibody;
Retinoid related orphan receptor gamma antibody;
Rorc antibody;
RORG antibody;
RORG_HUMAN antibody;
RZR gamma antibody;
RZRG antibody;
TOR antibody
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
