1817773-66-2
1817773-66-2
Chemical Structure
Bevurogant
Synonym(s): BI 730357
- CAS No.: 1817773-66-2
- Formula:C26H28N8O3S
- Molecular Weight:532.62
IUPAC Name: (S)-2-(4-cyclopropyl-6-methylpyrimidin-5-yl)-8-(1-cyclopropylethyl)-6-(((5-(methylsulfonyl)pyridin-2-yl)methyl)amino)pteridin-7(8H)-one
InChIKey: HVVHIBHBDCYLDI-HNNXBMFYSA-N
SMILES: C[C@@H](C1CC1)N2C3=NC(C4=C(C)N=CN=C4C5CC5)=NC=C3N=C(C2=O)NCC6=CC=C(C=N6)S(C)(=O)=O
Biological Activity: Bevurogant (BI 730357) is a retinoid-related orphan receptor-gamma t (RORγt) antagonist. Bevurogant can be used for the research of chronic inflammatory diseases[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Bevurogant | 99.54% | Bevurogant (BI 730357) is a retinoid-related orphan receptor-gamma t (RORγt) antagonist. Bevurogant can be used for the research of chronic inflammatory diseases. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. BAKONYI J, et, al. Compounds as modulators of ror gamma. US20150291607A1.
- [2]. Choi H, et al. The Effect of BI 730357 (Retinoic Acid-Related Orphan Receptor Gamma t Antagonist, Bevurogant) on the Pharmacokinetics of a Transporter Probe Cocktail, Including Digoxin, Furosemide, Metformin, and Rosuvastatin: An Open-Label, Non-randomized, 2-Period Fixed-Sequence Trial in Healthy Subjects. Clin Pharmacol Drug Dev. 2024 Feb;13(2):197-207. [Content Brief]
Keywords
