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Results for "

sedative and anticonvulsant

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Apoptosis (2) Biochemical Assay Reagents (1) Drug Derivative (4) Drug Intermediate (1) Environmental Pollutants (2) ERK (1) GABA Receptor (11) Glutathione Peroxidase (2) iGluR (1) NF-κB (2) PAK (1) Phytohormone (2) Platelet-activating Factor Receptor (PAFR) (1) Reactive Oxygen Species (ROS) (2) Reference Standards (2) Sodium Channel (1)
By Research Areas:	Cancer (2) Cardiovascular Disease (2) Inflammation/Immunology (4) Metabolic Disease (1) Neurological Disease (22)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-W013507

(rac)-Methyl jasmonate	Environmental Pollutants Glutathione Peroxidase Phytohormone Reactive Oxygen Species (ROS) NF-κB Apoptosis	Neurological Disease Inflammation/Immunology Cancer
(rac)-Methyl jasmonate is the racemate of Methyl jasmonate (HY-135663). Methyl jasmonate is a phytohormone that regulates the defense response of plants under biotic and biotic stress through jasmonate signaling pathway. Methyl jasmonate inhibits the activation of NF-κB signaling pathway. Methyl jasmonate can promote the mitochondrial ROS production, but also scavenges free radicals and reduces the oxidative stress. Methyl jasmonate exhibits anti-inflammatory, antitumor, anticonvulsant, antinociceptive and sedative activities .

HY-Y1673

Potassium bromide, 99%	Environmental Pollutants Biochemical Assay Reagents	Neurological Disease
Potassium bromide, 99% is a salt, widely used as an anticonvulsant and a sedative. Potassium bromide is a redox reagent that can be used to remove peripheral membrane proteins in molecular biology .

HY-B1229

Isovaleramide 1 Publications Verification 3-Methylbutanamide	GABA Receptor	Neurological Disease Metabolic Disease
Isovaleramide (3-Methylbutanamide) is an orally active anticonvulsant. Isovaleramide inhibits alcohol dehydrogenase (ADH) activity and regulates GABAergic system. Isovaleramide reduces acute kidney injury. Isovaleramide has antiepileptic, anxiolytic, sedative and hypnotic effects[1] .

HY-103505

CL 218872	GABA Receptor	Neurological Disease
CL 218872 is an orally active and selective ligand for the benzodiazepine receptor subtype BZ₁. CL 218872 exhibits anxiolytic, sedative and anticonvulsant activities. CL 218872 can be used in researches of anxiety related disorders and epilepsy .

HY-W050162

(E)-3,4,5-Trimethoxycinnamic acid 1 Publications Verification TMCA	GABA Receptor 5-HT Receptor	Neurological Disease
(E)-3,4,5-Trimethoxycinnamic acid (TMCA) is a cinnamic acid substituted by multi-methoxy groups. (E)-3,4,5-Trimethoxycinnamic acid is an orally active and potent GABA_A/BZ receptor agonist. (E)-3,4,5-Trimethoxycinnamic exhibits favourable binding affinity to 5-HT_2C and 5-HT_1A receptor, with IC₅₀ values of 2.5 and 7.6 μM, respectively. (E)-3,4,5-Trimethoxycinnamic acid shows anticonvulsant and sedative activity. (E)-3,4,5-Trimethoxycinnamic acid can be used for the research of insomnia, headache and epilepsy .

HY-N8303

Gardenin A	ERK PAK	Neurological Disease Inflammation/Immunology
Gardenin A is an orally active and synthetic PMF analogue with the neurotrophic effect for neurite outgrowth and neuronal differentiation. Gardenin A promotes neuritogenesis via activating MAPK/ERK, PKC, and PKA, but not TrkA, CREB signaling pathways. Gardenin A also has sedative, anxiolytic, antidepressant, and anticonvulsant effects .

HY-W013507R

(rac)-Methyl jasmonate (Standard)	Reference Standards NF-κB Reactive Oxygen Species (ROS) Glutathione Peroxidase Phytohormone Apoptosis	Neurological Disease Inflammation/Immunology Cancer
(rac)-Methyl jasmonate (Standard) is the analytical standard of Methyl jasmonate. This product is intended for research and analytical applications. (rac)-Methyl jasmonate is the racemate of Methyl jasmonate (HY-135663). Methyl jasmonate is a phytohormone that regulates the defense response of plants under biotic and biotic stress through jasmonate signaling pathway. Methyl jasmonate inhibits the activation of NF-κB signaling pathway. Methyl jasmonate can promote the mitochondrial ROS production, but also scavenges free radicals and reduces the oxidative stress. Methyl jasmonate exhibits anti-inflammatory, antitumor, anticonvulsant, antinociceptive and sedative activities .

HY-100377

Lvguidingan anticonvulsant 7903	Others	Neurological Disease
Lvguidingan is a potent *anticonvulsant* agent. Lvguidingan also has sedative-hypnotic, tranquilizing, and muscle-relaxing actions. Lvguidingan can be used as antiepileptic agent .

HY-171253

Clotizolam	Platelet-activating Factor Receptor (PAFR)	Neurological Disease
Clotizolam is a thienobenzodiazepine derivative that has antagonistic activity against platelet-activating factor (PAF). Clotizolam possesses sedative, anxiolytic, anticonvulsant,and muscle relaxant effects .

HY-119461

Capuride	Drug Derivative	Neurological Disease
Capuride is an orally active sedative agent. Capuride has anticonvulsant activity .

HY-107323

Bentazepam QM 6008; Thiadipone; Tiadipone	GABA Receptor	Neurological Disease
Bentazepam (Thiadipone) is a compound with short-action anxiolytic effect. Bentazepam shows anticonvulsant and sedative properties. Bentazepam can be used for the research of depressive disorder and anxiety .

HY-125508

CCD-3693	GABA Receptor	Neurological Disease
CCD-3693 is an orally active GABA receptor agonist. CCD-3693 has anxiolytic, anticonvulsant and sedative hypnotic activities and can be used in research related to neurological diseases .

HY-107323A

Bentazepam hydrochloride QM 6008 hydrochloride; Thiadipone hydrochloride; Tiadipone hydrochloride	GABA Receptor	Neurological Disease
Bentazepam (QM 6008, Thiadipone) hydrocholide is a compound with short-action anxiolytic effect. Bentazepam hydrocholide shows anticonvulsant and sedative properties. Bentazepam hydrocholide can be used for the research of depressive disorder and anxiety .

HY-119146

Zolazepam CI-716 free base	Drug Derivative	Neurological Disease
Zolazepam (CI-716 free base) is a benzodiazepine derivative with anxiolytic and anticonvulsant properties. Zolazepam combined with Tiletamine causes a decrease in ventilation, resulting in the development of respiratory acidosis. Zolazepam can be used as sedative and muscle relaxants .

HY-W197533

3-Hydroxymethyl-β-carboline	GABA Receptor	Neurological Disease
3-Hydroxymethyl-β-carboline antagonizes the anxiolytic and anticonvulsant actions of Diazepam and reverses the sedative action of Flurazepam. 3-Hydroxymethyl-β-carboline also antagonizes the cerebrovascular and cerebral metabolic depression produced by Flurazepam .

HY-106885

F 2692	Drug Derivative	Neurological Disease
F 2692 is an orally effective derivative of pyridazine. F 2692 has significant anti anxiety effects. F 2692 also has activities such as anticonvulsant, sedative, and muscle relaxant. F 2692 can be used for research on neurological disorders such as anxiety disorders .

HY-160978

Timelotem KC-7507 free base	GABA Receptor	Neurological Disease
Timelotem (KC-7507 free base) is a representative of a class of 1, 2-cyclo1, 4-benzodiazepines. Timelotem shows significant antipsychotic properties. Timelotem produces sedative, anti-anxiety and anti-convulsant effects by enhancing the action of the neurotransmitter gamma-aminobutyric acid (GABA). Timelotem can be used in studies of schizophrenia and other mental disorders .

HY-103505R

CL 218872 (Standard)	Reference Standards GABA Receptor	Neurological Disease
CL 218872 (Standard) is the analytical standard of CL 218872 (HY-103505). This product is intended for research and analytical applications. CL 218872 is an orally active and selective ligand for the benzodiazepine receptor subtype BZ1. CL 218872 exhibits anxiolytic, sedative and anticonvulsant activities. CL 218872 can be used in researches of anxiety related disorders and epilepsy .

HY-124148

Fenimide	Drug Intermediate	Neurological Disease Inflammation/Immunology
Fenimide is an antipsychotic agent. Fenimide shows sedative, anticonvulsant and anesthetic activity. Fenimide has also prevented formation of stress-induced gastric lesions in the rat .

HY-169651

GABA-IN-4	GABA Receptor	Neurological Disease
GABA-IN-4 (Compound 17) is a N-(indol-3-ylglyoxylyl)benzylamine derivative. GABA-IN-4 exhibits high affinity for the benzodiazepine receptor (BzR) (binding site in GABA_A receptor complex) with K_i value of 67 nM. Benzodiazepines are widely used as antianxiety, sedative-hypnotic and anticonvulsant agents .

HY-N16538

4-(Acetoxymethyl)phenyl glucoside	Drug Derivative	Cardiovascular Disease Neurological Disease
4-(Acetoxymethyl)phenyl glucoside is a type of gastrodin derivative that can cross the blood-brain barrier. 4-(Acetoxymethyl)phenyl glucoside exhibits sedative, anticonvulsant and analgesic effects in mouse models. 4-(Acetoxymethyl)phenyl glucoside can be used for research on senile cardiovascular and cerebrovascular diseases as well as brain nerve disorders .

HY-182548

BTS 72664	GABA Receptor Sodium Channel iGluR	Cardiovascular Disease Neurological Disease
BTS 72664 is a broad-spectrum, non-sedating, orally effective anticonvulsant. Its anticonvulsant effect mainly arises from enhancing GABA_A receptor (GABA_A receptor)-mediated chloride channel currents, while it exerts weak blocking effects on Na ⁺ channels (K_i = 350 μM) and NMDA receptors (NMDA receptor) (IC₅₀ = 43 μM). BTS 72664 prevents the elevation of extracellular glutamate, glycine and serine concentrations in neurons, reduces cerebral infarct size, promotes functional recovery, prevents multiple types of epileptic seizures, and has low sedative potential. BTS 72664 can be used for the research of epilepsy, stroke and migraine .

Potassium bromide, 99%	Biochemical Assay Reagents
Potassium bromide, 99% is a salt, widely used as an anticonvulsant and a sedative. Potassium bromide is a redox reagent that can be used to remove peripheral membrane proteins in molecular biology .

(rac)-Methyl jasmonate	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Environmental Pollutants Glutathione Peroxidase Phytohormone Reactive Oxygen Species (ROS) NF-κB Apoptosis
(rac)-Methyl jasmonate is the racemate of Methyl jasmonate (HY-135663). Methyl jasmonate is a phytohormone that regulates the defense response of plants under biotic and biotic stress through jasmonate signaling pathway. Methyl jasmonate inhibits the activation of NF-κB signaling pathway. Methyl jasmonate can promote the mitochondrial ROS production, but also scavenges free radicals and reduces the oxidative stress. Methyl jasmonate exhibits anti-inflammatory, antitumor, anticonvulsant, antinociceptive and sedative activities .

Isovaleramide 1 Publications Verification 3-Methylbutanamide	Structural Classification Natural Products other families Plants Source Classification	GABA Receptor
Isovaleramide (3-Methylbutanamide) is an orally active anticonvulsant. Isovaleramide inhibits alcohol dehydrogenase (ADH) activity and regulates GABAergic system. Isovaleramide reduces acute kidney injury. Isovaleramide has antiepileptic, anxiolytic, sedative and hypnotic effects[1] .

Gardenin A	Flavonoids Flavones Rutaceae Plants Citrus reticulata Blanco Source Classification	ERK PAK
Gardenin A is an orally active and synthetic PMF analogue with the neurotrophic effect for neurite outgrowth and neuronal differentiation. Gardenin A promotes neuritogenesis via activating MAPK/ERK, PKC, and PKA, but not TrkA, CREB signaling pathways. Gardenin A also has sedative, anxiolytic, antidepressant, and anticonvulsant effects .

(rac)-Methyl jasmonate (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards NF-κB Reactive Oxygen Species (ROS) Glutathione Peroxidase Phytohormone Apoptosis
(rac)-Methyl jasmonate (Standard) is the analytical standard of Methyl jasmonate. This product is intended for research and analytical applications. (rac)-Methyl jasmonate is the racemate of Methyl jasmonate (HY-135663). Methyl jasmonate is a phytohormone that regulates the defense response of plants under biotic and biotic stress through jasmonate signaling pathway. Methyl jasmonate inhibits the activation of NF-κB signaling pathway. Methyl jasmonate can promote the mitochondrial ROS production, but also scavenges free radicals and reduces the oxidative stress. Methyl jasmonate exhibits anti-inflammatory, antitumor, anticonvulsant, antinociceptive and sedative activities .

4-(Acetoxymethyl)phenyl glucoside	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source Classification	Drug Derivative
4-(Acetoxymethyl)phenyl glucoside is a type of gastrodin derivative that can cross the blood-brain barrier. 4-(Acetoxymethyl)phenyl glucoside exhibits sedative, anticonvulsant and analgesic effects in mouse models. 4-(Acetoxymethyl)phenyl glucoside can be used for research on senile cardiovascular and cerebrovascular diseases as well as brain nerve disorders .

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sedative and anticonvulsant

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Natural
Products