Capuride
Capuride is an orally active sedative agent. Capuride has anticonvulsant activity.
For research use only. We do not sell to patients.
- CAS No.: 5579-13-5
- Formula: C9H18N2O2
- Molecular Weight:186.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Capuride (p.o., rats) shows neurotoxicity with an ED50 of 232 mg/kg[2].
Capuride (49-71 mg/kg, i.p.) shows anticonvulsant activity in 6 Hz Psychomotor seizure mice[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Electrically (MES) and chemically (scMet) induced seizures in rats[2]
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Dosage:38-107 mg/kg
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Administration:Oral administration (p.o.)
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Result:ED50s: 54 mg/kg (MES model), 77 mg/kg (scMet model).
Chemical Information
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CAS No. 5579-13-5
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Molecular Weight 186.25
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Formula C9H18N2O2
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SMILES
CCC(C(C(NC(N)=O)=O)CC)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Goldstein L, et al. Quantitative EEG analysis of single-dose effect relationships in normal volunteers of Pacinox (capuride), a new antianxiety drug. Biological psychiatry, 1971, 3(2): 165-172. [Content Brief]
[2]. Jakob Avi Shimshoni, et al. Potent anticonvulsant urea derivatives of constitutional isomers of valproic acid. J Med Chem. 2007 Dec 13;50(25):6419-27. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)