184 Results for "

short-chain

" in MedChemExpress (MCE) Product Catalog:
Products (184)

184 Results for "short-chain" in MCE Product Catalog:

25
25 Publications Verification
Cat. No.: HY-N0455D
CAS No.: 80407-72-3
Synonyms: (S)-(+)-Arginine butanoate
Research Areas:  

Others

L-Arginine butanoate ((S)-(+)-Arginine butanoate) is a compound consisting of L-Arginine and butanoate. L-Arginine is one of the essential nutrients in the human body and participates in various biochemical processes. Butanoate is a short-chain fatty acid commonly used as a food additive and solvent in pharmaceutical formulations .
loading...
    loading...
6
6 Cited Publications
Cat. No.: HY-P1125
CAS No.: 300851-67-6
Research Areas:  

Others

4-CMTB is a selective free fatty acid receptor 2 (FFA2/GPR43) agonist and a positive allosteric modulator (pEC50=6.38) .
loading...
    loading...
5
5 Cited Publications
Cat. No.: HY-100216
CAS No.: 68181-17-9
Purity:  99.14%
Synonyms: SPDP Crosslinker; Py-ds-Prp-OSu
Target:  

ADC Linkers

Research Areas:  

Cancer

SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) .
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-134452
CAS No.: 2566-34-9
Purity:  ≥98.0%
Synonyms: α-(Methylamino)isobutyric acid
Research Areas:  

Cancer

MeAIB (α-(Methylamino)isobutyric acid) is a specific?substrate for amino acid transport system A (ATA1). ATA mediate the uptake of short-chain neutral amino acids in a Na +-dependent manner .
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-Y1325H
CAS No.: 6131-90-4
Sodium acetate trihydrate, meets analytical specification of Ph. Eur. BP USP FCC E262, ≤0.00002% Al is a carboxylic acid and short-chain fatty acid (SCFAs). Sodium acetate trihydrate activates AMPK, increases ROS, cleaved caspase 9, PPARα, downregulates SREBP-1c, ChREBP expression. Sodium acetate trihydrate exhibits antifungal activity against Saccharomyces cerevisiae W303-1A. Sodium acetate trihydrate regulates energy metabolism. Sodium acetate trihydrate has anticancer activity against gastric cancer. Sodium acetate trihydrate induces writhing reaction and ulcerative colitis. Sodium acetate trihydrate can be used in the researches for gastric cancer, ulcerative colitis, hepatic steatosis, and pain .
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-N7075
CAS No.: 9005-80-5
Inulin is an orally active prebiotic targeting the intestinal microbiota, selectively promoting the proliferation and activity of beneficial bacteria such as bifidobacteria and lactic acid bacteria, and playing a role in regulating the intestinal microecology. The functions of Inulin include: Fermentation by probiotics in the colon to produce short-chain fatty acids (such as butyrate and propionate), lowering the intestinal pH and inhibiting the overgrowth of harmful bacteria; Enhancing the intestinal barrier function and reducing endotoxin translocation; Directly scavenging free radicals (such as superoxide free radicals, hydroxyl free radicals) and activating antioxidant enzymes (SOD, CAT) to reduce oxidative stress. Inulin can also be used in the study of intestinal diseases (constipation, IBD), metabolic syndrome (diabetes, obesity) and liver damage by regulating glucose and lipid metabolism (such as reducing triglycerides, improving insulin sensitivity) and immune response (enhancing NK cell activity, inhibiting inflammatory factors)[1][2][3][4].
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-B1773A
CAS No.: 137-40-6
Sodium propionate is an orally active short-chain fatty acid. Sodium propionate can be produced by intestinal bacteria from the metabolism of dietary fiber. Sodium propionate increases PPAR-γ, inhibits NF-κB activation, and reduces COX-2 expression and NO production. Sodium propionate also induces Apoptosis and Autophagy. Sodium propionate reduces HSV-1-induced keratitis. Sodium propionate has anticancer effects against glioblastoma. Sodium propionate exhibits neuroprotective, antioxidant, and anti-inflammatory activities. Sodium propionate can be used in the research of spinal cord injury and Alzheimer's disease .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-19542
CAS No.: 124753-97-5
Synonyms: C6-Cer; N-Hexanoylsphingosine
Target:  

Apoptosis

Research Areas:  

Cancer

C6 Ceramide (C6-Cer) is a short-chain, cell-permeable ceramide pathway activator with anticancer activity. C6 Ceramide-mediated miR-29b expression participates in the progression of multiple myeloma through suppressing the proliferation, migration and angiogenesis of endothelial cells by targeting Akt signal pathway. C6 Ceramide exhibits multiple anti-cancer properties including cell cycle arrest, Apoptosis, inhibition of tumor growth and enhances the effects of chemotherapy in drug-resistant cancer cells. C6-ceramide can be used as an adjuvant for chemotherapeutic agents, to enhance anti-tumor effects .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-113266
CAS No.: 40225-14-7
Purity:  ≥95.0%
Valerylcarnitine is an endogenous metabolite, belonging to the short-chain acylcarnitines. Valerylcarnitine acts as a metabolomic biomarker for ionizing radiation exposure in nonhuman primates. Valerylcarnitine can be used for the research of type 1 diabetes .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P0033
CAS No.: 616204-22-9
Synonyms: Acetyl hexapeptide-3; Acetyl hexapeptide-8
Target:  

Calcium Channel

Research Areas:  

Neurological Disease

Argireline (Acetyl hexapeptide-3) is a non-toxic, skin-permeable, antiwrinkle peptide. Argireline significantly inhibits Ca 2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argireline has antiwrinkle and anti-aging activity .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-148104
CAS No.: 2332820-04-7
Purity:  99.49%
ACSS2-IN-2 is an acyl-CoA synthetase short-chain family member 2 (ACSS2) inhibitor. ACSS2-IN-2 can inhibit ACSS2 activity with an IC50 value of 3.8 nM. ACSS2-IN-2 can be used for the research of several diseases, such as viral infection, metabolic disorders, neuropsychiatric diseases, inflammatory/autoimmune conditions and cancer .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W011404
CAS No.: 60-01-5
Synonyms: Glyceryl tributyrate
Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed proagent of Butyric Acid. Tributyrin diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into the cell in vivo. Tributyrin has potent antiproliferative, proapoptotic and differentiation-inducing effects .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W012980
CAS No.: 503-74-2
Isovaleric acid is an oral active short-chain fatty acid that inhibits osteoclast differentiation by stimulating AMPK phosphorylation and promotes colonic smooth muscle relaxation by activating the cAMP/PKA pathway. Isovaleric acid can be used in research on skeletal diseases (such as osteoporosis) and intestinal disorders .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W015882
CAS No.: 646-07-1
Synonyms: Isocaproic acid
4-Methylpentanoic acid (Isocaproic Acid) is a short-chain fatty acid and a metabolite of 20 α-hydroxycholesterol (HY-12316) that can be detected in feces. The concentration of 4-Methylpentanoic acid is closely associated with several diseases, such as depression. 4-Methylpentanoic acid is also applicable to studies on cholesterol metabolism .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N2840
CAS No.: 488-44-8
Synonyms: Allodulcitol
Allitol (Allodulcitol) is an orally active rare sugar alcohol found in Itea virginica L, Tylopilus plumbeoviolaceus. Allitol has anti-obesity and hypoglycaemic activities. Allitol reduces carcass and total body fat mass, increases cecal weight, surface area, and short-chain fatty acid production, and upregulates cecal microbial enzymes linked to butyrate metabolism. Allitol can be used for the researches of obesity and diabetes .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-21191
CAS No.: 375-73-5
Synonyms: PFBS
Perfluorobutanesulfonic acid (PFBS) is a short-chain perfluoroalkyl substance and the main replacement for perfluorooctanesulfonic acid. Perfluorobutanesulfonic acid induces fat accumulation in human HepG2 hepatoma cells. Perfluorobutanesulfonic acid promotes lipid accumulation by activating PPARγ pathway and triggering oxidative stress, endoplasmic reticulum stress and calcium dyshomeostasis. Perfluorobutanesulfonic acid impairs reproduction and causes developmental disorders in offspring of Caenorhabditis elegans. Perfluorobutanesulfonic acid disrupts pancreatic organogenesis and lipid homeostasis in zebrafish embryos. Perfluorobutanesulfonic acid can be used in environmental toxicology, lipid metabolism and developmental toxicity studies .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W007894
CAS No.: 595-46-0
Dimethylmalonic acid is a short-chain dicarboxylic acid in human serum. Dimethylmalonic acid is also a volatile organic compound detected in alveolar breath .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-K2023

MCE In vivo OptiLNP RNA Transfection Reagent (Local Effect) is a ready-to-use transfection reagent based on LNP technology. It is designed for the efficient transfection of mRNA and short-chain RNA in experimental animals. The RNA functions locally.

loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P71092
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: QDPR; PKU2; Quinoid Dihydropteridine Reductase; short chain Dehydrogenase/Reductase Family 33C Member 1; SDR33C1; 6,7-Dihydropteridine Reductase; DHPR; short chain Dehydrogenase/Reductase Family 33C, Member 1; Dihydropteridine Reductase; Testis Secretory
Species:  
Source:  
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N7088
CAS No.: 512-69-6
Synonyms: Melitose
Raffinose (Melitose) regulates intestinal flora, inhibits TLR4-MyD88-NF-κB signaling pathway, and activates Nrf2 signaling pathway. Raffinose exhibits anti-inflammatory, antioxidant, and immunomodulatory activities. Raffinose is orally active .
loading...
    loading...