1. Apoptosis
  2. Apoptosis
  3. Tributyrin

Tributyrin (Synonyms: Glyceryl tributyrate)

Cat. No.: HY-W011404
Handling Instructions

Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid. Tributyrin diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into the cell in vivo. Tributyrin has potent antiproliferative, proapoptotic and differentiation-inducing effects.

For research use only. We do not sell to patients.

Tributyrin Chemical Structure

Tributyrin Chemical Structure

CAS No. : 60-01-5

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Description

Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid. Tributyrin diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into the cell in vivo. Tributyrin has potent antiproliferative, proapoptotic and differentiation-inducing effects[1].

Molecular Weight

302.36

Formula

C₁₅H₂₆O₆

CAS No.

60-01-5

SMILES

CCCC(OCC(OC(CCC)=O)COC(CCC)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (330.73 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3073 mL 16.5366 mL 33.0732 mL
5 mM 0.6615 mL 3.3073 mL 6.6146 mL
10 mM 0.3307 mL 1.6537 mL 3.3073 mL
*Please refer to the solubility information to select the appropriate solvent.
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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

TributyrinGlyceryl tributyrateApoptosisVitamin DCaco-2 cellprodrugantiproliferativeproapoptoticcell differentiationfatty acid triglyceride ApoptosisMiaPaca-2Inhibitorinhibitorinhibit

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