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4-CMTB 

Cat. No.: HY-P1125
Handling Instructions

4-CMTB is a selective free fatty acid receptor 2 (FFA2/GPR43) agonist and a positive allosteric modulator (pEC50=6.38).

For research use only. We do not sell to patients.

4-CMTB Chemical Structure

4-CMTB Chemical Structure

CAS No. : 300851-67-6

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Description

4-CMTB is a selective free fatty acid receptor 2 (FFA2/GPR43) agonist and a positive allosteric modulator (pEC50=6.38)[1].

In Vitro

4-CMTB is both a direct agonist and a positive allosteric modulator of the action of short-chain free fatty acids. 4-CMTB modulates the activity of short-chain fatty acids at FFA2 via the FFA2 second extracellular loop (ECL2)[1][2].

Molecular Weight

294.80

Formula

C₁₄H₁₅ClN₂OS

CAS No.

300851-67-6

SMILES

O=C(NC1=NC=CS1)C(C(C)C)C2=CC=C(Cl)C=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

4-CMTBOthersligandGPCRsECL2short-chainfreefattyacidsago-allostericInhibitorinhibitorinhibit

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