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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
stromelysin-1
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "stromelysin-1" in MCE Product Catalog:
1
1 Cited Publications
NNGH is a stromelysin-1 (MMP-3) inhibitor. MMP-3 is both a direct transcriptional target and a necessary contributor of the Wnt/β-catenin signaling pathway. Matrix metalloproteinases (MMPs) play a well-defined role in later stages of tumor progression [1].
Cat. No.: HY-P3699
CAS No.: 202273-56-1
Target:
Research Areas:
Cat. No.: HY-P3202
CAS No.: 79955-99-0
Synonyms: MMP-3; stromelysin-1
Target:
Research Areas:
Matrix metalloproteinase 3 (MMP-3) is a member of the class of zinc-dependent proteases that can degrade the extracellular matrix (ECM). Matrix metalloproteinase 3 palys an important role in the neuronal apoptotic process as well as in neuroinflammation. Matrix metalloproteinase 3 can be used in the study of neurodegenerative diseases including Alzheimer’s disease (AD) and Parkinson’s disease (PD) [1].
Cat. No.: HY-P3699A
Target:
Research Areas:
TNO003 TFA is a selective fluorogenic substrate for stromelysin-1 (MMP-3). TNO003 TFA has higher selectivity for MMP-3 than MMP-1, MMP-2, MMP-7, MMP-8, MMP-9 and MMP-13. TNO003 TFA can be used for the determination of stromelysin activity (Ex/Em = 360/490 nm) [1].
Cat. No.: HY-P73297
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MMP3; SL-1; Prev. STMY1; Matrix Metalloproteinase 3; Prev. STMY; Proteoglycanase; Matrix Metalloproteinase 3 (stromelysin 1, Progelatinase); stromelysin 1; stromelysin-1; CHDS6; Transin-1; STR1; MMP-3; Matrix Metallopeptidase 3; Matrix Metalloproteinase-3
Species:
Human
Source:
E. coli
Cat. No.: HY-P70139
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MMP3; SL-1; Prev. STMY1; Matrix Metalloproteinase 3; Prev. STMY; Proteoglycanase; Matrix Metalloproteinase 3 (stromelysin 1, Progelatinase); stromelysin 1; stromelysin-1; CHDS6; Transin-1; STR1; MMP-3; Matrix Metallopeptidase 3; Matrix Metalloproteinase-3
Species:
Human
Source:
HEK293
Cat. No.: HY-187685
CAS No.: 147485-09-4
Target:
Research Areas:
L 696418 is a MMP-3 inhibitor with a Ki value of 310 nM. L 696418 inhibits MMP-3 activity, thereby preventing the release of proteoglycans from cartilage. L 696418 reduces proteoglycan release in rabbit knee joints exposed to interleukin-1β (IL-1β). L 696418 can be used in research related to cartilage degradation [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
