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tomato fruits

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By Targets:	Autophagy (2) Biochemical Assay Reagents (1) CaSR (2) Cytochrome P450 (2) Endogenous Metabolite (3) Fungal (2) Microtubule/Tubulin (1) Mitophagy (2) NF-κB (2) Reactive Oxygen Species (ROS) (1) Reference Standards (3)
By Research Areas:	Cancer (5) Cardiovascular Disease (1) Infection (2) Inflammation/Immunology (2) Metabolic Disease (2)

Inhibitors & Agonists

Natural
Products

Targets Recommended: Tomato Spotted Wilt Virus (TSWV)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0287

Lycopene 15+ Cited Publications	Reactive Oxygen Species (ROS) Endogenous Metabolite	Cardiovascular Disease Cancer
Lycopene is naturally occurring carotenoids found in tomato, tomato products, and in other red fruits and vegetables; exhibits antioxidant effects.

HY-N0153

Naringin Maximum Cited Publications 24 Publications Verification Naringoside	Cytochrome P450 Autophagy Mitophagy Endogenous Metabolite	Inflammation/Immunology Cancer
Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities. Naringin also inhibits proliferation and invasion and induces apoptosis in human osteosarcoma cells by inhibiting zinc finger E-box binding homeobox 1 (Zeb1) .

HY-N0119

Naringin Dihydrochalcone 4 Publications Verification Naringin DC	NF-κB	Cancer
Naringin Dihydrochalcone is an artificial sweetener derived from naringin. Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities. Naringin suppresses NF-κB signaling pathway.

HY-121584

Lycoperodine-1 1 Publications Verification Cyclomethyltryptophan	CaSR	Metabolic Disease
Lycoperodine-1 (Cyclomethyltryptophan) is an active product that can be isolated from tomato fruits (Lycopersicon sculentum). Lycoperodine-1 act as an agonist of Ca ²⁺ sensing receptors (CaSR) .

HY-N0153R

Naringin (Standard) Maximum Cited Publications 24 Publications Verification Naringoside (Standard)	Endogenous Metabolite Cytochrome P450 Mitophagy Autophagy Reference Standards	Inflammation/Immunology Cancer
Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities. Naringin also inhibits proliferation and invasion and induces apoptosis in human osteosarcoma cells by inhibiting zinc finger E-box binding homeobox 1 (Zeb1) .

HY-121584R

Lycoperodine-1 (Standard) Cyclomethyltryptophan (Standard)	CaSR Reference Standards	Metabolic Disease
Lycoperodine-1 (Standard) is the analytical standard of Lycoperodine-1. This product is intended for research and analytical applications. Lycoperodine-1 (Cyclomethyltryptophan) is an active product that can be isolated from tomato fruits (Lycopersicon sculentum). Lycoperodine-1 act as an agonist of Ca2+ sensing receptors (CaSR) .

HY-124385

Tunaxanthin	Biochemical Assay Reagents	Others
Tunaxanthin is a xanthophyll, exists in fruits of various tomato strains and their hybrid. Tunaxanthin is also a carotenoid present in fish .

HY-N0119R

Naringin Dihydrochalcone (Standard) Naringin DC (Standard)	Reference Standards NF-κB	Cancer
Naringin Dihydrochalcone (Standard) is the analytical standard of Naringin Dihydrochalcone. This product is intended for research and analytical applications. Naringin Dihydrochalcone is an artificial sweetener derived from naringin. Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities. Naringin suppresses NF-κB signaling pathway.

HY-N16514

8(S)-HPETE	Others	Others
8(S)-HPETE, short for 8(S)-hydroperoxy-5Z,9E,11Z,14Z-eicosatetraenoic acid, is a major oxygenation product generated when arachidonic acid acts as a substrate for the lipoxygenase purified from ripe tomato fruits .

HY-176552

Tubulin polymerization-IN-83	Fungal Microtubule/Tubulin	Infection
Tubulin polymerization-IN-83 (Compound A23) is a flavonol derivative. Tubulin polymerization-IN-83 exhibits antifungal activity against various phytopathogenic fungi, with an EC₅₀ of 0.338 μg/mL against Botrytis cinerea. Tubulin polymerization-IN-83 exerts its effects by targeting β-tubulin, disrupting mycelial morphology, and increasing cell membrane permeability, with relatively low ecological and environmental risks .

HY-135442

Simeconazole	Fungal	Infection
Simeconazole is a demethylation inhibitor-class fungicide. Simeconazole prevents the infection of barley leaves by Blumeria graminis f sp hordei, inhibits the development of powdery mildew on barley and cucumber leaves, and exhibits cuticular membrane permeability in tomato fruits. Simeconazole can be used in research related to barley powdery mildew and cucumber powdery mildew .

Lycopene 15+ Cited Publications	Structural Classification Natural Products Classification of Application Fields Endocrine diseases Solanum lycopersicum L. Plants Endogenous metabolite Food Research Infection Human Gut Microbiota Metabolites Immune System Disorder Disease markers Pigments Solanaceae Disease Research Fields Cancer Source Classification	Reactive Oxygen Species (ROS) Endogenous Metabolite
Lycopene is naturally occurring carotenoids found in tomato, tomato products, and in other red fruits and vegetables; exhibits antioxidant effects.

Naringin Maximum Cited Publications 24 Publications Verification Naringoside	Citrus × aurantium Linnaeus Flavonoids Classification of Application Fields Leguminosae Flavonones Rutaceae Plants Endogenous metabolite Glycyrrhiza uralensis Fisch. Disease Research Fields Cancer	Cytochrome P450 Autophagy Mitophagy Endogenous Metabolite
Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities. Naringin also inhibits proliferation and invasion and induces apoptosis in human osteosarcoma cells by inhibiting zinc finger E-box binding homeobox 1 (Zeb1) .

Naringin Dihydrochalcone 4 Publications Verification Naringin DC	Flavonoids other families Classification of Application Fields Phenols Polyphenols Plants Dihydrochalcones Disease Research Fields Sweeteners Source Classification Cancer Food Research	NF-κB
Naringin Dihydrochalcone is an artificial sweetener derived from naringin. Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities. Naringin suppresses NF-κB signaling pathway.

Lycoperodine-1 1 Publications Verification Cyclomethyltryptophan	Alkaloids Solanum lycopersicum L. Solanaceae Plants Indole Alkaloids Source Classification	CaSR
Lycoperodine-1 (Cyclomethyltryptophan) is an active product that can be isolated from tomato fruits (Lycopersicon sculentum). Lycoperodine-1 act as an agonist of Ca ²⁺ sensing receptors (CaSR) .

Naringin (Standard) Maximum Cited Publications 24 Publications Verification Naringoside (Standard)	Structural Classification Citrus × aurantium Linnaeus Classification of Application Fields Rutaceae Plants Endogenous metabolite Flavonoids Leguminosae Flavonones Glycyrrhiza uralensis Fisch. Disease Research Fields Source Classification Cancer	Endogenous Metabolite Cytochrome P450 Mitophagy Autophagy Reference Standards
Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities. Naringin also inhibits proliferation and invasion and induces apoptosis in human osteosarcoma cells by inhibiting zinc finger E-box binding homeobox 1 (Zeb1) .

Lycoperodine-1 (Standard) Cyclomethyltryptophan (Standard)	Structural Classification Alkaloids Solanum lycopersicum L. Solanaceae Plants Indole Alkaloids Source Classification	CaSR Reference Standards
Lycoperodine-1 (Standard) is the analytical standard of Lycoperodine-1. This product is intended for research and analytical applications. Lycoperodine-1 (Cyclomethyltryptophan) is an active product that can be isolated from tomato fruits (Lycopersicon sculentum). Lycoperodine-1 act as an agonist of Ca2+ sensing receptors (CaSR) .

Tunaxanthin	Structural Classification Natural Products Solanum lycopersicum L. Solanaceae Plants Source Classification	Biochemical Assay Reagents
Tunaxanthin is a xanthophyll, exists in fruits of various tomato strains and their hybrid. Tunaxanthin is also a carotenoid present in fish .

Naringin Dihydrochalcone (Standard) Naringin DC (Standard)	Structural Classification Flavonoids other families Phenols Polyphenols Plants Dihydrochalcones Source Classification	Reference Standards NF-κB
Naringin Dihydrochalcone (Standard) is the analytical standard of Naringin Dihydrochalcone. This product is intended for research and analytical applications. Naringin Dihydrochalcone is an artificial sweetener derived from naringin. Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities. Naringin suppresses NF-κB signaling pathway.

8(S)-HPETE	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Others
8(S)-HPETE, short for 8(S)-hydroperoxy-5Z,9E,11Z,14Z-eicosatetraenoic acid, is a major oxygenation product generated when arachidonic acid acts as a substrate for the lipoxygenase purified from ripe tomato fruits .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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tomato fruits

Inhibitors & Agonists

NaturalProducts

Natural
Products