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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
trimethyl lock adapter
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "trimethyl lock adapter" in MCE Product Catalog:
Cat. No.: HY-184906
Target:
Research Areas:
Mal-PEG4-Val-Ala-Ph-2,2-dimethylpropanoic acid is a maleimide-functionalized PEG4-Val-Ala dipeptide linker bearing a trimethyl-locked adapter for exatecan conjugation, which enables thiol conjugation via the maleimide group and facilitates payload release. Mal-PEG4-Val-Ala-Ph-2,2-dimethylpropanoic acid is used in cancer research .
Cat. No.: HY-181679
Target:
Research Areas:
TML-2Cl is a dichloro-modified trimethyl lock adapter for antibody-drug conjugates and payload releaser.TML-2Cl undergoes 1,6-elimination followed by rapid self-cyclization to facilitate release of the payload Exatecan after cathepsin B cleavage of the associated linker.TML-2Cl exhibits high stability when conjugated to a drug and high intrinsic hydrophobicity.TML-2Cl can be used for the research of gastric carcinoma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
