5 Results for "

trypanosomatids

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "trypanosomatids" in MCE Product Catalog:

Cat. No.: HY-W040264
CAS No.: 911660-54-3
Synonyms: Lanostenol
24,25-Dihydrolanosterol is a naturally occurring tetracyclic Δ 8-triterpene alcohol that can be found in the seeds of Capsicum annuum. 24,25-Dihydrolanosterol is the initial carbocyclic sterol precursor in animals, fungi, and trypanosomatids, and participates in sterol synthesis .
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Cat. No.: HY-148205
CAS No.: 96304-42-6
Target:  

Drug Derivative

Research Areas:  

Others

Trypanothione is a bis-glutathionyl derivative, found in trypanosomatids. Trypanothione shows the protection against oxidative stress .
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Cat. No.: HY-148205A
CAS No.: 1899127-69-5
Target:  

Drug Derivative

Research Areas:  

Others

Trypanothione TFA is a bis-glutathionyl derivative, can be isolated from trypanosomatids. Trypanothione TFA itself or assisted by different enzymatic systems is involved in anti-oxidant defense, cell proliferation, removal of toxic compounds and metabolites and iron-sulfur metabolism .
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Cat. No.: HY-163003
Target:  

Parasite

Research Areas:  

Infection

Antitrypanosomal agent 19 (compound 10) is an orally available antitrypanosomal agent. Antitrypanosomal agent 19 effectively inhibits the growth of trypanosomatids T. b. brucei, T. b. gambiense and T. b. rhodesiense, mitigating the Human trypanosomiasis (HAT)-induced acute infectious toxicity in mice .
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Cat. No.: HY-165597
CAS No.: 2229043-42-7
Research Areas:  

Infection

NPD-008 is a tetrahydrophthalazinone-based phosphodiesterase inhibitor. It exerts antiparasitic activity by binding to the active site of TbrPDEB1 to block cAMP degradation, increasing intracellular cAMP levels in trypanosomatid parasites, disrupting cellular structure, and inhibiting cytokinesis. NPD-008 is used in research on Chagas disease, leishmaniasis, and human African trypanosomiasis .
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