96304-42-6
96304-42-6
Chemical Structure
Trypanothione
- CAS No.: 96304-42-6
- Formula:C27H47N9O10S2
- Molecular Weight:721.85
IUPAC Name: (2S,2'S)-5,5'-(((4R,23R)-5,8,19,22-tetraoxo-1,2-dithia-6,9,13,18,21-pentaazacyclotetracosane-4,23-diyl)bis(azanediyl))bis(2-amino-5-oxopentanoic acid)
InChIKey: LZMSXDHGHZKXJD-VJANTYMQSA-N
SMILES: OC([C@@H](N)CCC(N[C@@H]1C(NCC(NCCCCNCCCNC(CNC([C@H](CSSC1)NC(CC[C@H](N)C(O)=O)=O)=O)=O)=O)=O)=O)=O
Biological Activity: Trypanothione is a bis-glutathionyl derivative, found in trypanosomatids. Trypanothione shows the protection against oxidative stress[1][2][3].
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Trypanothione | Trypanothione is a bis-glutathionyl derivative, found in trypanosomatids. Trypanothione shows the protection against oxidative stress. | |||||||||||||||||||||
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References
- [1]. Manta B, et al. Trypanothione: a unique bis-glutathionyl derivative in trypanosomatids. Biochim Biophys Acta. 2013 May;1830(5):3199-216. [Content Brief]
- [2]. Fairlamb AH, et al. Metabolism and functions of trypanothione in the Kinetoplastida. Annu Rev Microbiol. 1992;46:695-729. [Content Brief]
- [3]. Krauth-Siegel RL, et al. The parasite-specific trypanothione metabolism of trypanosoma and leishmania. Biol Chem. 2003 Apr;384(4):539-49. [Content Brief]
