Antitrypanosomal agent 19
Antitrypanosomal agent 19 (compound 10) is an orally available antitrypanosomal agent. Antitrypanosomal agent 19 effectively inhibits the growth of trypanosomatids T. b. brucei, T. b. gambiense and T. b. rhodesiense, mitigating the Human trypanosomiasis (HAT)-induced acute infectious toxicity in mice.
For research use only. We do not sell to patients.
- Formula: C10H11N3O4S
- Molecular Weight:269.28
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
Trypanosome[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | CC50 |
>75 μM
Compound: 10
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Cytotoxicity against human HepG2 cells assessed as cell growth measured after 72 hrs mby MTT assay
Cytotoxicity against human HepG2 cells assessed as cell growth measured after 72 hrs mby MTT assay
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[PMID: 37984297] |
Chemical Information
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Molecular Weight 269.28
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Formula C10H11N3O4S
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SMILES
O=C(C1=CC=C([N+]([O-])=O)S1)NC/C=C/C(NC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antitrypanosomal agent 19 Related Classifications
HY-163003 Related Classifications
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