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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
tumor exosome
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "tumor exosome" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-N6796
CAS No.: 52665-74-4
Cat. No.: HY-116879
CAS No.: 1680193-58-1
Synonyms: (2E)-4-Oxo-2-nonen-8-ynal; alkynyl-4-ONE
4-Oxo-2-Nonenal Alkyne ((2E)-4-Oxo-2-nonen-8-ynal; alkynyl-4-ONE) is a functionalized lipid electrophile that conjugated to the exosomes via the reaction of amino and aldehyde groups. 4-Oxo-2-Nonenal Alkyne can be used in tumor exosomes determination .
Cat. No.: HY-P701877
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: EXOSC5; Ribosomal RNA-Processing Protein 46; exosome Component 5; exosome Complex Component RRP46; RRP46; exosome Component Rrp46; P12B; MGC12901; HRrp46p; exosome Complex Exonuclease RRP46; Rrp46p; CABAC; RRP41B; CML28; Chronic Myelogenous Leukemia tumor
Species:
Human
Source:
E. coli
Cat. No.: HY-P701878
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: EXOSC5; Ribosomal RNA-Processing Protein 46; exosome Component 5; exosome Complex Component RRP46; RRP46; exosome Component Rrp46; P12B; MGC12901; HRrp46p; exosome Complex Exonuclease RRP46; Rrp46p; CABAC; RRP41B; CML28; Chronic Myelogenous Leukemia tumor
Species:
Human
Source:
E. coli
Cat. No.: HY-P11891
Target:
Research Areas:
FM213 is a PD-L1 inhibitor with a human IC50 of 323 nM. FM213 blocks PD-1/PD-L1 protein-protein interactions, and promotes endocytosis and lysosome-dependent degradation of PD-L1 on the surface of cancer cells. FM213 binds to PD-L1 on cancer cells and exosomes, and enhances the recognition and killing of cancer cells by human PBMC. Combination of FM213 with the TIGIT inhibitor DTBP-3 (HY-P11903) enhances anti-tumor immunity. FM213 can be used in research related to non-small cell lung cancer .
Cat. No.: HY-182639
CAS No.: 1869033-49-7
Target:
Research Areas:
AM9928 is a monoacylglycerol lipase (MAGL) inhibitor with IC50 and Ki values of 8.9 nM and 7.3 nM, respectively. AM9928 blocks the adhesion and migration of triple-negative breast cancer (TNBC) cells, and inhibits the secretion of IL-6, IL-8 and VEGF-A by TNBC cells. AM9928 suppresses the activation of human brain microvascular endothelial cells (HBMECs) induced by TNBC-derived exosomes, and reduces the secretion of IL-8 and VEGF-A by HBMECs. AM9928 attenuates changes in blood-brain barrier permeability, inhibits tumor growth in the mammary fat pad, and reduces brain colonization of TNBC. AM9928 can be used in studies related to triple-negative breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
