Tetraethylene glycol monomethyl ether
Based on 1 Customer Validation
Tetraethylene glycol monomethyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 23783-42-8
- Formula: C9H20O5
- Molecular Weight:208.25
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All PROTAC Linkers Isoforms
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Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 23783-42-8
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Appearance Liquid (Density: 1.045 g/cm3)
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Molecular Weight 208.25
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Formula C9H20O5
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Color Colorless to light yellow
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SMILES
COCCOCCOCCOCCO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : ≥ 100 mg/mL (480.19 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.8019 mL | 24.0096 mL | 48.0192 mL | 120.0480 mL |
| 5 mM | 0.9604 mL | 4.8019 mL | 9.6038 mL | 24.0096 mL | |
| 10 mM | 0.4802 mL | 2.4010 mL | 4.8019 mL | 12.0048 mL | |
| 15 mM | 0.3201 mL | 1.6006 mL | 3.2013 mL | 8.0032 mL | |
| 20 mM | 0.2401 mL | 1.2005 mL | 2.4010 mL | 6.0024 mL | |
| 25 mM | 0.1921 mL | 0.9604 mL | 1.9208 mL | 4.8019 mL | |
| 30 mM | 0.1601 mL | 0.8003 mL | 1.6006 mL | 4.0016 mL | |
| 40 mM | 0.1200 mL | 0.6002 mL | 1.2005 mL | 3.0012 mL | |
| 50 mM | 0.0960 mL | 0.4802 mL | 0.9604 mL | 2.4010 mL | |
| 60 mM | 0.0800 mL | 0.4002 mL | 0.8003 mL | 2.0008 mL | |
| 80 mM | 0.0600 mL | 0.3001 mL | 0.6002 mL | 1.5006 mL | |
| 100 mM | 0.0480 mL | 0.2401 mL | 0.4802 mL | 1.2005 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.