Pentaethylene glycol monomethyl ether
Based on 1 Customer Validation
Pentaethylene glycol monomethyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.84%
- CAS No.: 23778-52-1
- Formula: C11H24O6
- Molecular Weight:252.30
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-W042625
Hexaethylene glycol monomethyl ether
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HY-W018365
Tetraethylene glycol monomethyl ether
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HY-140697
m-PEG5000-OH
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HY-W042657
Octaethylene glycol monomethyl ether
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HY-141217
m-PEG7-alcohol
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HY-140696
m-PEG2000-OH
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HY-120175
Nonaethylene glycol monomethyl ether
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HY-140696E
m-PEG1000-OH
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HY-140696B
m-PEG550-OH
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HY-140696C
m-PEG20000-OH
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HY-140696D
m-PEG10000-OH
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HY-140696H
m-PEG750-OH
All PROTAC Linkers Isoforms
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Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 23778-52-1
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Appearance Liquid (Density: 1.053±0.06 g/cm3)
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Molecular Weight 252.30
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Formula C11H24O6
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Color Colorless to light yellow
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SMILES
COCCOCCOCCOCCOCCO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 200 mg/mL (792.71 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9635 mL | 19.8177 mL | 39.6354 mL | 99.0884 mL |
| 5 mM | 0.7927 mL | 3.9635 mL | 7.9271 mL | 19.8177 mL | |
| 10 mM | 0.3964 mL | 1.9818 mL | 3.9635 mL | 9.9088 mL | |
| 15 mM | 0.2642 mL | 1.3212 mL | 2.6424 mL | 6.6059 mL | |
| 20 mM | 0.1982 mL | 0.9909 mL | 1.9818 mL | 4.9544 mL | |
| 25 mM | 0.1585 mL | 0.7927 mL | 1.5854 mL | 3.9635 mL | |
| 30 mM | 0.1321 mL | 0.6606 mL | 1.3212 mL | 3.3029 mL | |
| 40 mM | 0.0991 mL | 0.4954 mL | 0.9909 mL | 2.4772 mL | |
| 50 mM | 0.0793 mL | 0.3964 mL | 0.7927 mL | 1.9818 mL | |
| 60 mM | 0.0661 mL | 0.3303 mL | 0.6606 mL | 1.6515 mL | |
| 80 mM | 0.0495 mL | 0.2477 mL | 0.4954 mL | 1.2386 mL | |
| 100 mM | 0.0396 mL | 0.1982 mL | 0.3964 mL | 0.9909 mL |
Pentaethylene glycol monomethyl ether Related Classifications
HY-W042713 Related Classifications
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