Thalidomide-4-C3-NH2 hydrochloride
Thalidomide-4-C3-NH2 hydrochloride is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-C3-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs.
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- CAS No.: 2357110-84-8
- Formule: C16H18ClN3O4
- Masse moléculaire:351.78
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Voir tous les produits spécifiques à Isoform E3 Ligase Ligand-Linker Conjugates
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Activité biologique
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Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2357110-84-8
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Masse moléculaire 351.78
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Formule C16H18ClN3O4
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SMILES
O=C1NC(C(CC1)N2C(C3=CC=C(CCCN)C=C3C2=O)=O)=O.Cl
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Thalidomide-4-C3-NH2 hydrochloride Related Classifications
HY-139545 Related Classifications
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