Thalidomide-NH-C2-NH-C5-NH2
Thalidomide-NH-C2-NH-C5-NH2 is an E3 ligase ligand-linker conjugate that can be used for PROTAC synthesis. Thalidomide-NH-C2-NH-C5-NH2 serves as the E3 ligase ligand-linker conjugate moiety of PROTAC IRAK4 degrader-6 (HY-139317).
For research use only. We do not sell to patients.
- CAS No.: 2357108-46-2
- Formula: C20H27N5O4
- Molecular Weight:401.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Thalidomide-NH-C2-NH-C5-NH2 is the E3 ligase ligand-linker conjugate moiety of PROTAC IRAK4 degrader-6 (HY-139317). PROTAC IRAK4 degrader-6 (compound I-127) is a Cereblon-based IRAK4 PROTAC degrader that can be used in cancer-related research, such as studies on multiple myeloma[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2357108-46-2
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Molecular Weight 401.46
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Formula C20H27N5O4
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SMILES
NCCCCCNCCNC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Thalidomide-NH-C2-NH-C5-NH2 Related Classifications
HY-184672 Related Classifications
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