Tie2 kinase inhibitor 2
Based on 1 Customer Validation
Tie2 kinase inhibitor 2 (compound 7) is a selective Tie2 kinase inhibitor with an IC50 value of 1 μM. Tie2 kinase inhibitor 2 inhibits endothelial cell tube formation, and can be used for Tie2-mediated angiogenic disorders research.
For research use only. We do not sell to patients.
- Purity: 99.0%
- CAS No.: 1020412-97-8
- Formula: C31H35N3O5
- Molecular Weight:529.63
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Tie2 1 μM (IC50) |
Tie2 1.3 μM (IC50) |
Chemical Information
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CAS No. 1020412-97-8
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Appearance Solid
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Molecular Weight 529.63
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Formula C31H35N3O5
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Color White to light brown
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SMILES
O=C(C1=CC(C2=CC=C(CN(CC(N[C@H](C3CCCCC3)C)=O)C(OC4=CC=C(C)C=C4)=O)C=C2)=CN=C1)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (188.81 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8881 mL | 9.4406 mL | 18.8811 mL | 47.2028 mL |
| 5 mM | 0.3776 mL | 1.8881 mL | 3.7762 mL | 9.4406 mL | |
| 10 mM | 0.1888 mL | 0.9441 mL | 1.8881 mL | 4.7203 mL | |
| 15 mM | 0.1259 mL | 0.6294 mL | 1.2587 mL | 3.1469 mL | |
| 20 mM | 0.0944 mL | 0.4720 mL | 0.9441 mL | 2.3601 mL | |
| 25 mM | 0.0755 mL | 0.3776 mL | 0.7552 mL | 1.8881 mL | |
| 30 mM | 0.0629 mL | 0.3147 mL | 0.6294 mL | 1.5734 mL | |
| 40 mM | 0.0472 mL | 0.2360 mL | 0.4720 mL | 1.1801 mL | |
| 50 mM | 0.0378 mL | 0.1888 mL | 0.3776 mL | 0.9441 mL | |
| 60 mM | 0.0315 mL | 0.1573 mL | 0.3147 mL | 0.7867 mL | |
| 80 mM | 0.0236 mL | 0.1180 mL | 0.2360 mL | 0.5900 mL | |
| 100 mM | 0.0189 mL | 0.0944 mL | 0.1888 mL | 0.4720 mL |
Tie2 kinase inhibitor 2 Related Classifications
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