Xrcc6 - X-ray repair cross complementing 6 Gene

Also Known as Ku70; G22p1; Kup70

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25019

Summary

Contributes to double-stranded DNA binding activity. Involved in brain development; cellular hyperosmotic salinity response; and cellular response to X-ray. Located in cytoplasm and nucleolus. Part of protein-containing complex. Orthologous to human XRCC6 (X-ray repair cross complementing 6). [provided by Alliance of Genome Resources, Apr 2022]

Xrcc6 Products (1)

mRNA Protein Name
NM_139080.2 NP_620780.2 X-ray repair cross-complementing protein 6

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
contributes to double-stranded DNA binding IDA
IDA: Inferred from direct assay
14576192 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
14576192 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular hyperosmotic salinity response IDA
IDA: Inferred from direct assay
11175667 RGD
involved in cellular response to X-ray IDA
IDA: Inferred from direct assay
11175667 RGD
Cellular Component GO Annotation Evidence References Source
part of protein-containing complex IDA
IDA: Inferred from direct assay
14576192 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

X-ray repair cross-complementing protein 6

  • Ku70 DNA-binding component of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa)

  • X-ray repair complementing defective repair in Chinese hamster cells 6

  • thyroid autoantigen

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15901 XRCC6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19756 Xrcc6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26253 Xrcc6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Xrcc6 NCBI NCBI:2547