Gli2 - GLI family zinc finger 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 304729

Summary

Predicted to enable several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; promoter-specific chromatin binding activity; and zinc ion binding activity. Involved in prostate gland development and response to mechanical stimulus. Predicted to be located in several cellular components, including axoneme; ciliary tip; and nuclear lumen. Predicted to be active in nucleus. Biomarker of esophageal atresia/tracheoesophageal fistula. Human ortholog(s) of this gene implicated in Culler-Jones syndrome; holoprosencephaly 9; and spina bifida. Orthologous to human GLI2 (Gli family zinc finger 2). [provided by Alliance of Genome Resources, Apr 2022]

Gli2 Products (1)

mRNA Protein Name
NM_001107169.1 NP_001100639.1 zinc finger protein GLI2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in positive regulation of collagen biosynthetic process IMP
IMP: Inferred from mutant phenotype
26823780 RGD
involved in prostate gland development IEP
IEP: Inferred from expression pattern
15328011 RGD
involved in response to mechanical stimulus IEP
IEP: Inferred from expression pattern
16943241 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

zinc finger protein GLI2

  • GLI-Kruppel family member GLI2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-13901 GANT 61 99.80% Unkown
HY-RS05475 GLI2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-12487 NL-103 Inhibitor / Unkown
HY-137567 Prostaglandin E1 ethanolamide Activator / Unkown
HY-183335 SMO-IN-6 / Unkown
HY-RS05481 GLIS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20743 Gli2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21582 Glis2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27255 Gli2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28100 Glis2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gli2 NCBI NCBI:2736