YM-44781 free acid
YM-44781 free acid is a non-peptide neuropeptide receptor antagonist with efficient NK(2) and NK(1) receptor antagonist activity. YM-44781 exhibits significant binding affinity on the NK(2) receptor (pKi = 9.94) and also on the NK(1) receptor Higher binding affinity (pKi = 9.09). In addition, YM-44781 also showed significant inhibitory effects on bladder contraction induced by selective NK(1) receptor agonists.
For research use only. We do not sell to patients.
- CAS No.: 173943-29-8
- Formula: C31H32Cl2FN3O2
- Molecular Weight:568.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
Chemical Information
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CAS No. 173943-29-8
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Molecular Weight 568.51
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Formula C31H32Cl2FN3O2
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SMILES
O=C(N(CC(CCN1CCC2(CC1)NC(CC3=C2C=CC=C3)=O)C4=CC=C(C(Cl)=C4)Cl)C)C5=CC=C(C=C5)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
YM-44781 free acid Related Classifications
HY-129296 Related Classifications
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