10-Formyltetrahydrofolic acid disodium 

10-Formyltetrahydrofolic acid disodium is a form of tetrahydrofolic acid that acts as a donor of formyl groups in anabolism. 10-Formyltetrahydrofolic acid disodium can be used as a substrate for formyltransferase reactions and is involved in the biosynthesis of purines^[1].

10-Formyltetrahydrofolic acid disodium in the liver of male Sprague-Dawley rats increases significantly after 30 and 60 minutes by administration of 1.3 mmol/kg methionine^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

517.40

C₂₀H₂₁N₇Na₂O₇

914800-65-0

Solid

Yellow to brown

O=C(O[Na])CC[C@@H](C(O[Na])=O)NC(C1=CC=C(N(CC2NC3=C(NC(N)=NC3=O)NC2)C=O)C=C1)=O

Shipping with dry ice.

-80°C, protect from light, stored under nitrogen

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months.

• [1]. Donald W Horne, et al. Neither methionine nor nitrous oxide inactivation of methionine synthase affect the concentration of 5,10-methylenetetrahydrofolate in rat liver. J Nutr. 2003 Feb;133(2):476-8.  [Content Brief]