11-Deoxyglycyrrhetinic acid sodium
11-Deoxyglycyrrhetinic acid sodium is a compound that exhibits anti-inflammatory activity. 11-Deoxyglycyrrhetinic acid sodium activates the Ca2+/voltage-gated K+ large conductance (BK) (cbv1 + β1) channels cloned from rat cerebral artery myocytes with the EC50 of 53 μM.
For research use only. We do not sell to patients.
- CAS No.: 1148013-87-9
- Formula: C30H47NaO3
- Molecular Weight:478.68
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
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CAS No. 1148013-87-9
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Molecular Weight 478.68
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Formula C30H47NaO3
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SMILES
C[C@]12[C@@](CC=C3[C@]2(CC[C@@]4([C@@]3([H])C[C@](C)(CC4)C(O[Na])=O)C)C)([H])[C@@]5([C@@](C(C)([C@H](CC5)O)C)([H])CC1)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Siviy SM, et al. Noradrenergic modulation of play in Sprague-Dawley and F344 rats. Psychopharmacology (Berl). 2023 Jul 10. [Content Brief]
[2]. Bukiya AN, et al. Cerebrovascular dilation via selective targeting of the cholane steroid-recognition site in the BK channel β1-subunit by a novel nonsteroidal agent. Mol Pharmacol. 2013;83(5):1030-1044. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)