18β-Glycyrrhetyl-3-O-sulfate-d₃ (Synonyms: Glycyrrhetic acid 3-O-hydrogen sulfate-d₃)

Cat. No.: HY-148682S2: FAQs
Data Sheet Handling Instructions

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18β-Glycyrrhetyl-3-O-sulfate-d₃ is the deuterium labeled 18β-Glycyrrhetyl-3-O-sulfate (HY-148682)[1].

For research use only. We do not sell to patients.

18β-Glycyrrhetyl-3-O-sulfate-d<sub>3</sub> Chemical Structure

18β-Glycyrrhetyl-3-O-sulfate-d₃ Chemical Structure

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Other Forms of 18β-Glycyrrhetyl-3-O-sulfate-d₃:

18β-Glycyrrhetyl-3-O-sulfate In-stock
18β-Glycyrrhetyl-3-O-sulfate-d₂ Get quote

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References
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Description

18β-Glycyrrhetyl-3-O-sulfate-d₃ is the deuterium labeled 18β-Glycyrrhetyl-3-O-sulfate (HY-148682)[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

553.77

Formula

C₃₀H₄₃D₃O₇S

SMILES

C[C@]12[C@]3(C([C@@]4([H])[C@@](CC3)(CC[C@@](C)(C4)C(O)=O)C)=CC([C@]1([H])[C@@]5([C@@](C(C)([C@](C([2H])([2H])C5)([2H])OS(=O)(O)=O)C)([H])CC2)C)=O)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (180.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.8058 mL	9.0290 mL	18.0580 mL
5 mM	0.3612 mL	1.8058 mL	3.6116 mL
10 mM	0.1806 mL	0.9029 mL	1.8058 mL

View the Complete Stock Solution Preparation Table

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-229. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.8058 mL	9.0290 mL	18.0580 mL	45.1451 mL
	5 mM	0.3612 mL	1.8058 mL	3.6116 mL	9.0290 mL
	10 mM	0.1806 mL	0.9029 mL	1.8058 mL	4.5145 mL
	15 mM	0.1204 mL	0.6019 mL	1.2039 mL	3.0097 mL
	20 mM	0.0903 mL	0.4515 mL	0.9029 mL	2.2573 mL
	25 mM	0.0722 mL	0.3612 mL	0.7223 mL	1.8058 mL
	30 mM	0.0602 mL	0.3010 mL	0.6019 mL	1.5048 mL
	40 mM	0.0451 mL	0.2257 mL	0.4515 mL	1.1286 mL
	50 mM	0.0361 mL	0.1806 mL	0.3612 mL	0.9029 mL
	60 mM	0.0301 mL	0.1505 mL	0.3010 mL	0.7524 mL
	80 mM	0.0226 mL	0.1129 mL	0.2257 mL	0.5643 mL
	100 mM	0.0181 mL	0.0903 mL	0.1806 mL	0.4515 mL

18β-Glycyrrhetyl-3-O-sulfate-d₃ Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

18β-Glycyrrhetyl-3-O-sulfate-d₃Glycyrrhetic acid 3-O-hydrogen sulfate-d₃Isotope-Labeled CompoundsInhibitorinhibitorinhibit

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18β-Glycyrrhetyl-3-O-sulfate-d3 (Synonyms: Glycyrrhetic acid 3-O-hydrogen sulfate-d3)

Other Forms of 18β-Glycyrrhetyl-3-O-sulfate-d3:

18β-Glycyrrhetyl-3-O-sulfate-d3 Related Antibodies