2-(3-amino-3-carboxypropyl)Histidine synthase

2-(3-Amino-3-carboxypropyl)histidine synthase (EC 2.5.1.108) is a [4Fe-4S] enzyme that modifies a histidine residue of translation elongation factor 2 (EF2) via a 3-amino-3-carboxypropyl radical. 2-(3-Amino-3-carboxypropyl)histidine synthase (EC 2.5.1.108) is involved in the biosynthesis of diphthamide.

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