2-Amino-2'-fluoro-2'-deoxyadenosine
2-Amino-2'-fluoro-2'-deoxyadenosine is a building block of nucleic acid.
For research use only. We do not sell to patients.
- Purity: 98.80%
- CAS No.: 134444-47-6
- Formula: C10H13FN6O3
- Molecular Weight:284.25
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | EC50 |
>10 μM
Compound: 22
|
compound was tested in vitro for anti HBV activity in HepG2 2.2.15 cells
compound was tested in vitro for anti HBV activity in HepG2 2.2.15 cells
|
[PMID: 9276020] |
| HepG2 | IC50 |
>180 μM
Compound: 22
|
The cytotoxicity against 2.2.15 cells expressed as IC50
The cytotoxicity against 2.2.15 cells expressed as IC50
|
[PMID: 9276020] |
Chemical Information
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CAS No. 134444-47-6
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Appearance Solid
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Molecular Weight 284.25
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Formula C10H13FN6O3
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Color White to off-white
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SMILES
O[C@H]1[C@@H](F)[C@H](N2C3=NC(N)=NC(N)=C3N=C2)O[C@@H]1CO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 8.33 mg/mL (29.31 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5180 mL | 17.5901 mL | 35.1803 mL | 87.9507 mL |
| 5 mM | 0.7036 mL | 3.5180 mL | 7.0361 mL | 17.5901 mL | |
| 10 mM | 0.3518 mL | 1.7590 mL | 3.5180 mL | 8.7951 mL | |
| 15 mM | 0.2345 mL | 1.1727 mL | 2.3454 mL | 5.8634 mL | |
| 20 mM | 0.1759 mL | 0.8795 mL | 1.7590 mL | 4.3975 mL | |
| 25 mM | 0.1407 mL | 0.7036 mL | 1.4072 mL | 3.5180 mL |