2'-RIBOTAC-U recruiter-linker
Based on 1 Customer Validation
2'-RIBOTAC-U recruiter-linker (Compound 9) consists of RNase L recruiter and linker. 2'-RIBOTAC-U recruiter-linker is reacted separately with 2’-azido-uridine or 5’-azidomethyl-uridine via copper-catalyzed click chemistry, resulting in the formation of 2’-RIBOTAC-U and 5’-RIBOTAC-U, respectively. 2’-RIBOTAC-U has anti-SARS-CoV-2 activity.
For research use only. We do not sell to patients.
- Purity : 99.96%
- Formula: C33H38N2O9S
- Molecular Weight:638.73
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
All DNA/RNA Synthesis Isoforms
More
Biological Activity
Description
Chemical Information
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Appearance Solid
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Molecular Weight 638.73
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Formula C33H38N2O9S
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SMILES
OC1=CC(/C=C2SC(NC3=CC=CC=C3)=C(C(OCC)=O)C\2=O)=CC=C1OCCOCCOCCOCCNC(CCC#C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (156.56 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5656 mL | 7.8280 mL | 15.6561 mL | 39.1402 mL |
| 5 mM | 0.3131 mL | 1.5656 mL | 3.1312 mL | 7.8280 mL | |
| 10 mM | 0.1566 mL | 0.7828 mL | 1.5656 mL | 3.9140 mL | |
| 15 mM | 0.1044 mL | 0.5219 mL | 1.0437 mL | 2.6093 mL | |
| 20 mM | 0.0783 mL | 0.3914 mL | 0.7828 mL | 1.9570 mL | |
| 25 mM | 0.0626 mL | 0.3131 mL | 0.6262 mL | 1.5656 mL | |
| 30 mM | 0.0522 mL | 0.2609 mL | 0.5219 mL | 1.3047 mL | |
| 40 mM | 0.0391 mL | 0.1957 mL | 0.3914 mL | 0.9785 mL | |
| 50 mM | 0.0313 mL | 0.1566 mL | 0.3131 mL | 0.7828 mL | |
| 60 mM | 0.0261 mL | 0.1305 mL | 0.2609 mL | 0.6523 mL | |
| 80 mM | 0.0196 mL | 0.0979 mL | 0.1957 mL | 0.4893 mL | |
| 100 mM | 0.0157 mL | 0.0783 mL | 0.1566 mL | 0.3914 mL |