1. Cell Cycle/DNA Damage
  2. CDK
  3. rel-(2S,3R)-Voruciclib

rel-(2S,3R)-Voruciclib is the (2S,3R)-enantiomer of Voruciclib. (2S,3R)-Voruciclib is an orally active CDK inhibitor.

For research use only. We do not sell to patients.

rel-(2S,3R)-Voruciclib Chemical Structure

rel-(2S,3R)-Voruciclib Chemical Structure

CAS No. : 1253731-24-6

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Description

rel-(2S,3R)-Voruciclib is the (2S,3R)-enantiomer of Voruciclib. (2S,3R)-Voruciclib is an orally active CDK inhibitor[1].

IC50 & Target

CDK[1]

In Vitro

rel-(2S,3R)-Voruciclib (Compound B, formula I) is used in combination with a compound capable of inhibiting EGFR kinase activity and Gemcitabine to treat pancreatic cancer[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

469.84

Formula

C22H19ClF3NO5

CAS No.
SMILES

ClC1=CC(C(F)(F)F)=CC=C1C(OC2=C(C(O)=CC(O)=C23)[C@H]([C@H]4CO)CCN4C)=CC3=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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rel-(2S,3R)-Voruciclib Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
rel-(2S,3R)-Voruciclib
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HY-12422C
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