3,29-O-Dibenzoyloxykarounidiol
Based on 1 Customer Validation
3,29-O-Dibenzoyloxykarounidiol (Karounidiol dibenzoate) is a multiflorane-type triterpene benzoate that inhibits Phorbol 12-myristate 13-acetate (TPA) (HY-18739)-induced Epstein-Barr virus early antigen activation and exhibits tumor-promotion inhibitory activity. 3,29-O-Dibenzoyloxykarounidiol is used in cancer-related research.
For research use only. We do not sell to patients.
- Purity: 99.79%
- CAS No.: 389122-01-4
- Formula: C44H56O4
- Molecular Weight:648.91
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
3,29-O-Dibenzoyloxykarounidiol (Karounidiol dibenzoate) (compound 2) (10-1000 mol ratio/TPA; 48 h) inhibits Phorbol 12-myristate 13-acetate (TPA) (HY-18739)-induced Epstein-Barr virus early antigen activation in Raji cells, with an inhibition rate of 70.3% at 1000 mol ratio/TPA[1].
3,29-O-Dibenzoyloxykarounidiol (compound 36) (10-1000 mol ratio relative to TPA; 48 h) inhibits TPA-induced EBV-EA activation in Raji cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 389122-01-4
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Appearance Solid
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Molecular Weight 648.91
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Formula C44H56O4
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Color White to off-white
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SMILES
CC1(C)[C@H](OC(C2=CC=CC=C2)=O)CC[C@]3(C)C4=CC[C@@]5(C)[C@]6([H])C[C@](C)(COC(C7=CC=CC=C7)=O)CC[C@@](C)6CC[C@@](C)5C4=CC[C@@]13[H]
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Synonyms
Karounidiol dibenzoate
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
Ethanol : 2 mg/mL (3.08 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Ukiya M, et al. Inhibitory effects of cucurbitane glycosides and other triterpenoids from the fruit of Momordica grosvenori on epstein-barr virus early antigen induced by tumor promoter 12-O-tetradecanoylphorbol-13-acetate. Journal of agricultural and food chemistry. 2002 Nov 06;50(23):6710-5. [Content Brief]
[2]. Akihisa T, et al. Anti-tumor promoting effects of multiflorane-type triterpenoids and cytotoxic activity of karounidiol against human cancer cell lines. Cancer letters. 2001 Nov 08;173(1):9-14. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol | 1 mM | 1.5410 mL | 7.7052 mL | 15.4105 mL | 38.5261 mL |
3,29-O-Dibenzoyloxykarounidiol Related Classifications
HY-N7691 Related Classifications
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